THE PURSER WELLNESS LIBRARY

Let’s explore Vitamin B12 — lab reference

A COURSE FOR YOUR CURIOSITYMethylation & B vitamins

4 chapters, at your pace

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707 discoveries for your curiosity54 matching listings grouped; alternative sources stay available.

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Gene referenceSep 23, 2026

MTHFD1

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… MTHFR, SHMT1 and SLC19A1 and asks about current methylated-vitamin exposure. The practical question is how the whole folate/B12 pattern fits the person’s findings and tolerance, rather than treating every named gene as a separate supplemen…

Gene referenceSep 23, 2026

SHMT1

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…together instead of treating a folate result as an isolated vitamin issue. How Dr. Purser connects the pieces His wider map connects methylation with downstream sulfur handling and glutathione production. Learning the connection helps you d…

Gene referenceSep 23, 2026

TCN2

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TCN2 appears in Dr. Also called: Transcobalamin II B12 must be carried as well as consumed TCN2 appears in Dr. Purser’s homocysteine and methylation map because it concerns the transport of B12. The teaching distinction is between eating or…

YouTubeAug 6, 2026

OVER-METHYLATION - Are Your B Vitamins Hurting You?

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Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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InstagramJul 11, 2026

Could an overlooked lab marker be providing valuable insight into your health?

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Could an overlooked lab marker be providing valuable insight into your health? Understanding your homocysteine level may help you and your healthcare provider identify opportunities to support cardiovascular health, healthy methylation, an

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FacebookJun 15, 2026

What if one overlooked lab marker is telling you more about your health than you realize?

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What if one overlooked lab marker is telling you more about your health than you realize? Most people have never heard of homocysteine. Yet when homocysteine levels are elevated, it may signal that critical pathways involving methylation,

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FacebookMay 23, 2026

👋 Ever stared at your lab results and thought, “What am I even looking at here?”

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👋 Ever stared at your lab results and thought, “What am I even looking at here?” We hear that all the time with our CMA with Redox testing. Patients get TWO pages of results, and without a clear explanation it can feel overwhelming. In th

FacebookApr 28, 2026

Most people don’t realize how much vitamin deficiencies can quietly affect how they feel day to day. Low energy,…

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Most people don’t realize how much vitamin deficiencies can quietly affect how they feel day to day. Low energy, brain fog, weakened immunity—these can all be signs your body isn’t getting what it needs. Understanding why these deficiencies

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