Let’s explore “pain”

This report overview covers type I interferon signaling, pain, inflammation, and the management approaches discussed in the report.

This report overview covers interleukin-15 receptor subunit alpha, IL-15 signaling, natural killer cells, CD8+ T cells, and the report’s discussion of pain.

PURSER WELLNESSFrom Fibromyalgia to Feeling FantasticA conversation with Dr. Purser

In this consultation review, Jackson sat down with longtime Purser Wellness patient Lois Schweigert to go over her latest intracellular micronutrient (CMA) test results. After years of dealing with fibromyalgia, pain, gut issues, and inconsistent energy, Lois has made remarkable progress. Her newest CMA shows ZERO deficiencies — her best results ever — and it perfectly matches how great she’s been feeling. We discuss: • Her consistent weight training and dramatically improved recovery (thanks to catalase!) • Key optimization tweaks: amino acids, omega-3s, chromium, inositol, and glutathione • Blood sugar stability • Sleep support and overnight recovery • How trauma & stress affect your nutrient levels • Why intracellular testing is so unique and powerful If you’re dealing with chronic symptoms, poor workout recovery, or just want to optimize your health, this conversation is packed with practical insights from real patient results. 👉 Ready to get your own CMA? Visit danpursermd.com or comment “CMA” below and we’ll send you info. #PurserWellness #Fibromyalgia #RootCauseHealth #CMATest #FunctionalMedicine This video is for educational purposes only and is based on Dr. Dan Purser’s protocols. Not medical advice. Always consult with your healthcare provider. Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSWhat is VARS? Super Antioxidant Protection?A conversation with Dr. Purser

🔬 What is VARS? Why the VARS Trio (Glutathione + SOD + Catalase) is a game-changer for inflammation, recovery & fibromyalgia. Jackson Larkin sits down with Lois Schweiger to break down Dr. Dan Purser MD’s VARS line — Validated, Absorbable, Reduced, and Stable antioxidants. Learn the science behind VARS Glutathione, VARS SOD (from deep-sea algae near volcanic vents), and the newest VARS Catalase (Nrf2 activator from seaweed). Discover: • How the VARS Triad works together in the mitochondria to fight oxidative stress and cytokines • Why Catalase dramatically improved post-workout recovery (especially leg day!) • Genetics, homocysteine, PEMT, and why many with fibro benefit from this protocol • The importance of CMA (intracellular) testing and when to retest • Real patient results, including severe inflammation cases Perfect for anyone dealing with chronic pain, inflammation, slow recovery, or looking for root-cause support. **June Anniversary Special**: $100 off Genetic + CMA testing — one order will be fully reimbursed! 👉 Learn more & shop VARS supplements: danpursermd.com #VARSGlutathione #Fibromyalgia #Antioxidants #ChronicInflammation #PurserWellness #Catalase #SOD Timestamps: 00:00 Intro & What Does VARS Mean? 01:45 The Science of the VARS Triad 12:00 Who Needs the Trio? 14:00 Catalase & Workout Recovery Stories 20:00 Genetics, Homocysteine & Testing Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSFrom Bedridden to Thriving: Our Real Fibromyalgia JourneyA conversation with Dr. Purser

🎉 June Anniversary Special at Purser Wellness! Join Dr. Dan Purser MD’s team — Chantel (Chicky), Denise Purser, and Lois Schweigert from End Fibro with Natural Options — for an honest, heartfelt conversation about living well with fibromyalgia. We share real-life stories of flares, recovery, and ongoing improvement using Dr. Purser’s protocol. From severe teenage fibromyalgia to thriving as grandmothers, we discuss how the VARS Trio (Glutathione, SOD, and the game-changing Catalase) helps manage inflammation, cytokines, and hydrogen peroxide — plus practical tips on low-copper diet, serving sizes, gym recovery, weight loss, and consistency over perfection. Topics covered: • How to handle fibro flares quickly (catalase + SOD stories) • The importance of intracellular testing (CMA) & genetics • Low-copper eating guidelines & why serving size matters • Building strength and muscle after years of pain • Why we keep improving year after year 🔥 June Special: $100 off Genetic Testing + CMA (deepest discount of the year). One lucky order will be fully reimbursed! 👉 Order tests & supplements: https://danpursermd.com (or link in comments) If you or someone you love deals with fibromyalgia, chronic pain, fatigue, or inflammation, this episode is full of hope and actionable advice. 💬 Drop your biggest takeaway or question below — we read every comment! Timestamps: 00:00 - Intro & June Anniversary Sale 02:30 - Real flare story & catalase rescue 06:00 - Long-term improvement on the protocol 12:00 - Starting slow with supplements (topical tips) 23:00 - Low-copper diet & food list tips 36:00 - Gym recovery & building muscle 50:00 - Weight loss benefits & consistency #Fibromyalgia #ChronicPain #NaturalWellness #PurserWellness #FibroRecovery #LowCopperDiet Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

A subscriber episode from Purser Wellness on Substack, covering pain and wellbeing.

A subscriber post from Purser Wellness on Substack, covering testing and nutrients, pain and wellbeing.

Why elevated soluble IL-2 receptor levels drive chronic inflammation and pain in sarcoidosis — and what actually helps quiet the fire

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors MissFrom the reading room

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation. This is not fringe theory. It is the clinical reality I have

PURSER WELLNESSCope with Homocysteine Like a Pro!A conversation with Dr. Purser

High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even infertility. Genetics play a big role—there are 17 SNPs that can lock homocysteine in place—but vitamin deficiencies can make it worse. The real breakthrough isn’t lowering homocysteine itself but calming the cytokines it triggers, like IL-8 and MCP-1. That’s why VARS Glutathione, the only patented oral form proven to work, is so powerful—it lowers those cy

PURSER WELLNESSHow To Know If You Have High Homocysteine?A conversation with Dr. Purser

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

PURSER WELLNESSEBV and Fibromyalgia Related??A conversation with Dr. Purser

Just because you have EBV antibodies doesn’t mean it’s active—it usually means you’ve built immunity. The real issue? Most fibromyalgia patients have low reduced glutathione, which viruses like EBV intentionally suppress. That’s why symptoms overlap: fatigue, pain, immune dysfunction. Fix the glutathione issue, and you can support recovery on a deeper level.