THE PURSER WELLNESS LIBRARY

Let’s explore Anxiety

A COURSE FOR YOUR CURIOSITYA little clarity for mind & mood

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New to this subject? Start with this free introduction.Are Genetics Causing Your Anxiety?

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Health BlogMay 12, 2021

Why do I need methylated B Vitamins?

In the description

Many vitamins and minerals go through the methylation cycle meaning a methyl group is added to a molecule to turn it into its active form. Individuals with MTHFR and other genetic methylation errors are unable to efficiently create the methylated versions of those certain vitamins and minerals. Those with MTHFR specifically cannot make enough 5-MTHF, an activated form of folate, which in turn prohibits the ability to methylate other vitamins. These errors can lead to a number of cellular deficiencies which can cause chronic fatigue, anxiety, depression (BASICALLY MAKE YOU FEEL LIKE A SLUG) and

Health BlogMar 13, 2026

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

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Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model, which explains why homo

Health BlogApr 6, 2026

MTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss

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— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation. This is not fringe theory. It is the clinical reality I have

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