Let’s explore “Apolipoprotein B — lab reference”

Classify by evidence, zygosity, phenotype, and clinical actionability rather than a numeric range.

Dan and Jackson discuss methylated B vitamins, the term overmethylation, and questions to ask when your response to a supplement changes.

Are your B vitamins making you feel worse instead of better? Methylated B vitamins can be incredibly helpful for energy, homocysteine metabolism, neurological health, and many essential processes. But the right nutrient can become the wron

PURSER WELLNESSOVER-METHYLATION - Are Your B Vitamins Hurting You?A conversation with Dr. Purser

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Could an overlooked lab marker be providing valuable insight into your health? Understanding your homocysteine level may help you and your healthcare provider identify opportunities to support cardiovascular health, healthy methylation, an

A subscriber post from Purser Wellness on Substack, covering genetics and methylation.

A subscriber post from Purser Wellness on Substack, covering genetics and methylation.

What if one overlooked lab marker is telling you more about your health than you realize? Most people have never heard of homocysteine. Yet when homocysteine levels are elevated, it may signal that critical pathways involving methylation,

👋 Ever stared at your lab results and thought, “What am I even looking at here?” We hear that all the time with our CMA with Redox testing. Patients get TWO pages of results, and without a clear explanation it can feel overwhelming. In th

Can’t absorb iron no matter what you try? 😣 It might not be the iron — it’s your B vitamins. Fix the deficiency → fix the absorption.

If iron transfusions and pills aren’t working, the problem might be B vitamin deficiencies. Without enough B vitamins (like choline, biotin, or folate) or vitamin C, your body can’t absorb iron properly. Fixing these first can often restore

If you feel exhausted, irritable, or worse after taking methylated B vitamins, you may be overmethylating. Too many methyl groups can act like a “toxic overload,” leaving you sleepy or edgy. The fix is simple: stop high-dose methyl B’s and