THE PURSER WELLNESS LIBRARY

Let’s explore homocysteine

A COURSE FOR YOUR CURIOSITYHomocysteine: follow the connections

5 chapters, at your pace

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New to this subject? Start with this free introduction.The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

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Gene referenceSep 17, 2026

MTHFR

In the reference guide

Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.

Health BlogMar 13, 2026

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

In the title

Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model, which explains why homo

SubstackMay 28, 2026

Autism Spectrum Disorder, Homocysteine, Interleukin-8, and Monocyte Chemoattractant Protein-1: Elevated Biomarkers and Impaired Detoxification in Affected Children

In the title

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, mind, mood, and sleep.

SubstackMar 2, 2026

Can Glutathione Reverse Kidney Disease, Lower Blood Pressure, and Calm Cytokine Storms? What High Homocysteine May Be Doing to Your Arteries, Kidneys, and Fertility

In the title

The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step

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