THE PURSER WELLNESS LIBRARY

Let’s explore A1298C

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59 discoveries for your curiosity2 matching listings grouped; alternative sources stay available.

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YouTubeJan 6, 2026

What is MTHFR? What can YOU do about it?

In the description

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

YouTubeJan 5, 2026

What is MTHFR?

In the description

Dr. Purser explains the diagnosis and treatment of MTHFR (methylenteterahydrofolate reductase enzyme deficiency disease). Learn the genetic component of this illness (such as C677T or A1298C) and how it affects the body's inability of methylation to convert carbohydrates into ATP (Adenosine Triphosphate). Discover how the complex enzyme pathways of the Krebs cycle and citric acid cycle convert carbohydrate molecules into ATP molecules in the mitochondria. Explore the relationship of MTHFR to vitamin and hormone deficiencies while understanding how vitamin supplements can replace key missing (u

Health BlogApr 6, 2026

MTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss

In the article

…ies at least one MTHFR polymorphism (most commonly C677T or A1298C). These single-nucleotide changes reduce the enzyme methylenetetrahydrofolate reductase activity by 30–70%, impairing the conversion of folate into its active form (5-methyl…

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Health BlogMar 13, 2026

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

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Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model, which explains why homo

YouTubeJan 6, 2026

Glutathione and Your Ability To Detox?

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Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine storms. That’s why VARS Glutathione is such a breakthrough: it’s reduced, functional, and proven to lower harmful cytokines like IL-8 and MCP-1, giving your body the detox power it needs. After 15 years of research and real patient results, it’s the only oral glutathione that actually works where it matters—inside your cells.

YouTubeJan 5, 2026

What Causes Chronic Fatigue Syndrome?

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Do you know what causes chronic fatigue? Dr. Purser explains the top causes of Chronic Fatigue Syndrome (CFS) and shares what steps to take to feel normal again. Discover why CFS is a symptom of underlying conditions and what the treatment of underlying causes of CFS includes. Dr. Purser dispels the myth of medication deficiency related to CFS symptoms. Discover the relationship of nutritional deficiencies, hormone imbalance, and poorly understood genetic causes from MTHFR deficiency to fatigue. Learn what contributes to fatigue when the absorption of Vitamin B12, folate, pantothenate, and oth

Best match puts all-term matches before partial matches and related reading. Matching long titles across sources are grouped when access is the same. Search covers published titles, descriptions, and available article text. Substack subscriber titles and public summaries are included; full subscriber content opens on Substack. Video transcripts are added when available.