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You eat something sweet. Your energy shoots up. Then suddenly you are exhausted, foggy, irritable, and reaching for something else to get you through the day. That cycle deserves a closer look. MTHFR variants can influence folate meta

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

🙌 We're Back on the Main Dan Purser MD Facebook Page! Hey everyone! We wanted to give you a quick update. You may have seen our post letting you know we are back after losing access to our main Dan Purser MD Facebook page for the past wee

Dr. Dan Purser here with an important update from Purser Wellness. Earlier this week we were deplatformed on a major platform right after discussing groundbreaking findings from our homocysteine research — particularly its connections to ASD, ADHD, cytokine issues, and inflammatory conditions like polymyalgia rheumatica (PMR). Despite losing access to our old page (and nearly 200,000 followers), we’re back stronger with a brand new official page! ✅ Follow our new official Facebook page here: https://www.facebook.com/purserwellness We’re keeping things focused and continuing our important work on root-cause wellness, intracellular nutrient deficiencies, genetics, glutathione/SOD balance, and more. ### Where to Stay Connected: - Substack (Daily research articles & in-depth content): https://substack.com/PurserWellness or https://danpursermd.substack.com - YouTube – Live streams and full recordings will continue here (plus TikTok, Instagram, and podcast platforms) Dr. Purser’s message is clear: We will not stop the research. “I’ll quit when I die… and maybe not even then.” If you’ve been following our work on homocysteine, MTHFR, cytokine problems, hormone optimization, and functional medicine protocols, please: - Like and follow the new Facebook page - Subscribe to Substack - Share this video with friends and patients who need this information Thank you for your incredible support during this transition. Your follows and shares help us keep delivering the cutting-edge research no one else is doing. 👉 New Facebook Page: https://www.facebook.com/purserwellness Purser Wellness Root-Cause Medicine • Genetics • Homocysteine Research danpursermd.com #DrDanPurser #PurserWellness #Homocysteine #FunctionalMedicine #RootCauseHealth #CytokineResearch #ASD #ADHD #MTHFR

What if one tiny genetic variation could quietly influence how your body detoxifies, processes nutrients, and even supports your mental health—and most people have never heard of it? MTHFR isn’t just another health buzzword. It’s a conversa

In this powerful live session, Dr. Dan Purser MD reveals why conventional pediatric medicine often falls short and shares his proven Purser Method® for helping children with autism spectrum traits, severe ADHD, chronic inflammation, and developmental delays. Drawing from over 43 years of clinical experience, Dr. Purser explains: Why genetic testing (especially MTHFR and related SNPs) is the essential first step How to use targeted, active-form nutrients instead of generic vitamins The role of leucovorin (high-dose folinic acid) and when it makes a real difference Practical ways to reduce toxin load and calm the inflammatory response Smart strategies around vaccination and detoxification support Dr. Purser emphasizes that kids are not little adults — their developing systems need precise, individualized care. Parents and practitioners will walk away with actionable steps that address root causes rather than just managing symptoms. Whether your child is struggling with speech delays, meltdowns, focus issues, or recurrent health problems, this episode offers real hope through biochemistry done right. Resources Mentioned: Pediatric MTHFR formulas: https://www.PhysicianDesigned.com Book a consultation: http://www.DanPurserMD.com Dr. Purser’s books on Amazon: https://www.amazon.com/-/e/B00BIKSGVQ If you’re a parent tired of “there’s nothing more we can do,” or a practitioner looking for better tools, this episode is for you. Timestamps available in the full video. Subscribe, leave a review, and share this with any parent who needs to hear it. The kids deserve better answers. Dan Purser MD – Root Cause Inflammation & Genetic Optimization #MTHFR #Autism #ADHD #ChildrensHealth #Leucovorin #FunctionalMedicine #Pediatrics Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

The different versions of B12 may be HARMING you way more than they could be benefiting you. Remember, 4 forms of B12: Cyanocobalamin (bad), Mehtylcobalamin (important but can overmethylate), Adenosylcobalamin and Hydroxycobalamin (these ar

Struggling with constant fatigue? MTHFR gene mutations could be the missing link. Discover how understanding your genetics can help you reclaim your energy and feel your best! Find out more at PurserWellness.com today!

Struggling with MTHFR and not sure where to start? Discover real solutions with Purser Wellness Coach Jackson Larkin at PurserWellness.com. Take the first step toward lasting relief and reclaim your health today!

The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step https://danpursermd.substack.com/p/can-glutathione-reverse-kidney-disease?utm_source=youtube

This is a clip from https://danpursermd.substack.com/p/high-homocysteine-mthfr-mutations?utm_source=youtube_shorts See the full video: https://www.youtube.com/watch?v=HuQbQ1IqNIM #shorts #substack

This is a clip from https://danpursermd.substack.com/p/high-homocysteine-mthfr-mutations?utm_source=youtube_shorts See the full video: https://www.youtube.com/watch?v=HuQbQ1IqNIM #shorts #substack