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…ship to CCL3 and CCL4 helps explain why several recruitment signals can overlap during an inflammatory episode. A CCL5 marker cannot identify the trigger on its own. A question to bring to your visit Which symptoms, exposures or diagnoses g…

…e pieces together Dr. Purser’s panel places IL-16 among pro-inflammatory signals. The teaching value is to connect recruitment with the larger inflammatory picture instead of assigning a diagnosis to a numbered cytokine. Current symptoms, e…

…nflammation and promotion of fibrosis. Also called: Repair signals can also promote scarring TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effe…

…ert homocysteine to methionine, especially in the liver and kidneys. Choline, phosphatidylcholine and betaine have connected but distinct roles; they are not interchangeable products. Homocysteine The junction between two routes Remethylat…

…a major driver of heart attacks, strokes, hypertension, and kidney failure. If you want the deep dive on this science, read my textbook, HOMOCYSTEINE. Oddly enough, the core secret isn't just how to lower elevated homocysteine levels—that’s…

…rser explains how CD14 works with MD-2 and TLR4 to activate inflammatory signals such as NF-κB. This connects bacterial exposure, gut-barrier questions, monocyte activation, and downstream cytokines. Bring these questions to your visit Ask…

…f other conditions such as thyroid or adrenal gland issues, kidney disease or alcohol dependence. What are the Symptoms of High Blood Pressure? High blood pressure can develop slowly, with no symptoms. Meanwhile, it may be quietly damaging …

… immune signaling, and pain. How the pieces connect Immune signals and oxidative stress are research topics in pain. Persistent pain can have many causes, so ask which explanation fits your symptoms and findings. Pain is an experience, no…

Chronic inflammatory response syndrome, or CIRS, is a term used in some clinical discussions of persistent symptoms after environmental exposures.

Inclusion body myositis, or IBM, involves progressive muscle weakness with inflammatory and degenerative features.

Explore the allergy response and the immune signals discussed in Dr. Purser’s alpha-gal report.

Follow Dr. Purser’s discussion of interferons and other immune signals in lupus.