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…iscusses TGF-β in fibrosis and scarring, including selected homocysteine-related contexts. This is a reason to identify the organ and clinical process involved rather than treating every elevated inflammatory marker as the same problem. A c…

…ere the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approac…

…ere the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and the VARS Triad: VARS Glutathione, VARS SOD, and VARS Catalase. He gives glutathione a central place in his approac…

…ed so you can find the subjects that matter to you. MTHFR. Homocysteine. Cytokines. Nutrients. Antioxidants. These conversations connect. Now you have a place to explore those connections at your own pace. Search a topic. Watch a video. …

…ystem and doing whatever the screen dictates. Many of my fellow physicians admit they’ve simply become "EMR docs" who have lost the ability to reason deeply. The Reality of MTHFR, Homocysteine, and Cytokines These physicians know almost zer…

…C1, the gene involved in digestive histamine breakdown. Follow the pathway Dr. Purser discusses rs2391191, also described as Arg30Lys, alongside glutamate signaling and research on mood and cognition. D-serine helps NMDA receptors respond;…

…a wider network rather than the only cause of migraine. Follow the pathway His teaching connects cytokines, homocysteine, oxidative stress, and the trigeminal pain pathway. Conventional migraine discussions include triptans and CGRP-direct…

…lls that remove debris and participate in inflammation. Follow the pathway Dr. Purser follows the CCL2–CCR2 pathway through blood-vessel, kidney, and metabolic inflammation. He discusses homocysteine, NF-κB signaling, and reactive oxygen s…

…soluble IL-6 receptors and the gp130 signaling protein. Follow the pathway Dr. Purser discusses classic signaling, trans-signaling, JAK/STAT3, and the liver’s production of C-reactive protein. He also connects homocysteine and oxidative st…

…a chemokine, a signal that guides immune-cell movement. Follow the pathway Dr. Purser connects IL-8 with inflammatory activity in barrier tissues, blood vessels, and lungs. He discusses monocyte activation, homocysteine, and reactive oxyge…

… + Catalase) helps with inflammation and recovery Practical low-copper diet tips and why serving size matters Getting back into the gym and building strength after years of pain The power of consistency over perfection This is real talk fr…

…ens your detox pathways. When methylation, glutathione, and homocysteine balance are already struggling (especially if you have MTHFR variants), your body can’t clear toxins as well. That leads to more inflammation, leaky gut, and yes — glu…