PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
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What’s searchable?PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
SOD1 helps convert superoxide inside cells as part of the body’s antioxidant defenses.
SOD2 works in mitochondria as part of the body’s antioxidant defenses.
SOD3 works outside cells as part of the body’s antioxidant defenses.
Follow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine.
Explore the history, production signals, nutrient context and monitoring that shape Dr. Purser’s hormone assessment.
GSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1.
Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.
Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.
Dan and Jackson discuss the Algevity ingredient, Nrf2, antioxidant research, and VARS Catalase, including an update on the study’s publication status.
Dr. Purser’s subscriber report on MAO-A, genetic terminology, and the anxiety-related questions discussed in the public introduction.
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