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Report teachingOct 2, 2026
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See how crystals and immune signals play different roles in a gout flare. Understand the connection Gout begins with monosodium urate crystals. Immune signals amplify the response to those crystals and help produce the redness, swelling, a…

Report teachingOct 2, 2026
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…is teaching connects shoulder and hip stiffness with immune signals. Understand the connection Polymyalgia rheumatica, or PMR, often causes shoulder and hip-girdle pain with substantial morning stiffness. Similar symptoms can have other ca…

Report teachingAug 16, 2026
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Explore Th17 cells, mucosal immunity, the rs2275913 promoter variant, and inflammatory conditions.

Report teachingOct 2, 2026
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…myositis, or IBM, involves progressive muscle weakness with inflammatory and degenerative features. Understand the connection Inclusion body myositis, or IBM, involves progressive muscle weakness with inflammatory and degenerative features…

Report teachingOct 2, 2026
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Scleritis is painful inflammation of the white outer wall of the eye and can occur with other inflammatory conditions.

Gene referenceSep 23, 2026
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…e network that connects T-cell help, antibody responses and inflammatory activity. Also called: IL-21, Interleukin 21 A link between T-cell help and immune responses IL21 encodes a cytokine involved in regulating lymphocytes, including B-ce…

Gene referenceSep 23, 2026
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…ze immune-cell traffic in lymphoid tissues and some chronic inflammatory settings. Also called: Guiding B cells to organized immune sites CXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps org…

Gene referenceSep 23, 2026
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…age-associated molecular pattern, or DAMP, participating in inflammatory signaling. Also called: A cellular protein that can act as a danger signal HMGB1 normally has functions inside the cell nucleus. When released outside cells in partic…

Gene referenceSep 23, 2026
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IL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one. Also called: The immune system al…

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