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YouTube·YouTube publication: Jul 2, 2025

What’s transsulfuration? It’s your body’s way of turning inflammatory homocysteine into glutathione

Inflammation
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Original sourceDan Purser MD on YouTube

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YouTube captions · Unreviewed · Imported 2026-09-23

Captions can mishear medical terms, names, and doses. Check the recording for context. Each timestamp opens that moment on YouTube.

4 timestamped passages

0:02

What is trans sulfuration? I don't even know. Transuleration is is moving sulfur groups around. So you're trying to you're trying to convert the transuleration pathway is about converting homoyine which is incredibly inflammatory. Probably the worst inflammatory molecule in your body next

0:18

to radioactive iodine or something like that or or or flaming lava chip or something. Um but it's the most inflammatory cardiovascular um and and um it's just bad. It causes vascular inflammation like crazy and

0:34

you're converting it to the best thing in your body which is glutathione. If people have low glutathione levels on their intracellular testing, we see it all the time. They have probably some problem with their transuleration pathway. It CBS uh snip is a big part of

0:50

it. It's the gateway in a number of ways to entering the transforation pathway and making it work. Um, it's powered by B6 or pyodoxine. really critical.

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Dr. Purser places the VARS Triad—VARS Glutathione, VARS SOD and VARS Catalase—alongside MTHFR Daily at the center of his homocysteine and cytokine support approach. He emphasizes VARS Glutathione as a foundational functional-support component across his genetic SNP teaching.

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A LITTLE CLARITY

Understand the terms

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Homocysteine and methylation→CBS→Iodine→

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Glutathione, from the beginning

Mentions glutathione in the captions.

Inflammation topicWatch at 0:34 ↗
Meet your antioxidant network

Mentions glutathione in the captions.

Inflammation topicWatch at 0:34 ↗
Homocysteine: follow the connections

Mentions homocysteine.

Inflammation topic

Connections follow subject mentions. Read or watch the source for context.

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Inflammation & antioxidants

Follow the conversations on homocysteine, glutathione, antioxidant defenses, and redox balance.

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A term in this discussion

PURSER WELLNESSCBSFrom the reading room
Gene referenceSep 23, 2026

CBS

CBS is the gene symbol used for Cystathionine Beta-Synthase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Genetics

A term in this discussion

PURSER WELLNESSHomocysteine and methylationFrom the reading room
Learning essentialsSep 23, 2026

Homocysteine and methylation

Follow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine.

Testing

A term in this discussion

PURSER WELLNESSIodineFrom the reading room
Nutrient referenceSep 17, 2026

Iodine

Is needed to make thyroid hormones.

Testing

More on Meet your antioxidant network

PURSER WELLNESSCTHFrom the reading room
Gene referenceSep 23, 2026

CTH

CTH is the gene symbol used for Cystathionine Gamma-Lyase. This page connects its terminology with the topics in the Purser Wellness teaching library.

Genetics
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