Skip to content
Back to the library
YouTube·YouTube publication: May 27, 2025

If you have any methylation issues, you won’t process glutathione properly. Bad!

GeneticsInflammation
Open on YouTube
Video shape
From the original video description

Original sourceDan Purser MD on YouTube

Read the conversation.

YouTube captions · Unreviewed · Imported 2026-09-24

Captions can mishear medical terms, names, and doses. Check the recording for context. Each timestamp opens that moment on YouTube.

5 timestamped passages

0:02

Are there other deficiencies that will also cause problems with the trans? Oh, big time. Yeah. On our cellular micronutrient assay, it's really intracellular. I don't they call it cellular, but it's intracellular. Um, you might have significant deficiency of B6, which I already talked about, or glutathione, that's the end result. Um,

0:17

or glycine. Here's the ones that will hurt you. Glycine, glutamine, methionine, or serene. Um, so there's nine essential amino acids, which you can only get through your diet. Just to name them real quick, histadine, isolucine, lucine, lysine, methionine, phenyl alanine, thriionine, tryptophan,

0:34

and vein. And tryptophan is really interesting because it affects your ability. You make you make serotonin and melatonin from tryptophan. So if you're low on tryptophan, you can't make serotonin or melatonin. You'll be depressed and you'll have insomnia. So you be grumpy and tired all the time.

0:50

Wow. So um but the 11 essential 11 non-essential amino acids meaning you create them in your body are alanine, arginine, asparagene, aspartic acid, cyine, glutamic acid, glutamine, glycine, proline, serarene, and tyrrosine. So the four of those that are really critical for the transuleration

1:07

pathway, they're all non-essential. There's cyine or knack. They're glutamine, glycine or serarene. If you're low in any of those, your transforation pathway screwed

PURSER WELLNESS · PRACTICE & SHOP

Explore your next step.

VARS Glutathione Capsules product packagingPHYSICIAN DESIGNEDVARS Glutathione CapsulesCapsule product informationView productVARS Liposomal Glutathione product packagingPHYSICIAN DESIGNEDVARS Liposomal GlutathioneLiquid product informationView productTESTING & CONSULTATIONGenetic testing + consultationExplore the available testing bundlesExplore testing

Product and testing details from our practice and shop. Discuss what fits your needs with your clinician. Current labels, availability and pricing are shown on the linked pages.

ONE MORE CONNECTION MADE

Keep your curiosity going.

A LITTLE CLARITY

Understand the terms

Open a short reference guide.

Homocysteine and methylation→Arginine→Glycine→

FOLLOW YOUR CURIOSITY

Go deeper into this discussion

Glutathione, from the beginning

Mentions glutathione in the captions.

Inflammation topicWatch at 0:02 ↗
Meet your antioxidant network

Mentions glutathione in the captions.

Inflammation topicWatch at 0:02 ↗
Methylation & B vitamins

Mentions methylation.

Genetics topic

Connections follow subject mentions. Read or watch the source for context.

FOLLOW THE THREAD

Genetics & methylation

Make sense of the vocabulary. Explore MTHFR, genetic variants, and the conversations around methylation.

Explore this topic
A note on the archive

These are the original author’s words and perspectives. Older material may reflect earlier teaching. Use the source and publication date for context.

MORE FROM PURSER WELLNESS

Genetic testing + consultationExplore your inherited patterns.
Physician DesignedMeet the products behind the teaching.
CMA testing + consultationExplore intracellular nutrient testing.

Keep following the thread.

More to explore

A term in this discussion

PURSER WELLNESSHomocysteine and methylationFrom the reading room
Learning essentialsSep 23, 2026

Homocysteine and methylation

Follow Dr. Purser’s teaching on folate, B12, sulfur pathways and antioxidant support around homocysteine.

Testing

A term in this discussion

PURSER WELLNESSL-MethionineFrom the reading room
Nutrient referenceSep 23, 2026

L-Methionine

An amino acid used in protein synthesis and other metabolic processes.

Testing

More on Meet your antioxidant network

PURSER WELLNESSDan Purser MD - Live Q&A and Round Up!A conversation with Dr. Purser
YouTubeSep 6, 2026

Dan Purser MD - Live Q&A and Round Up!

Come chat with Dan Purser MD and Jackson Larkin about all things Purser Wellness - Catch up on new testing, products, books, and MORE!

CC Searchable captions
Wellness

More on Meet your antioxidant network

PURSER WELLNESSFrom Bedridden to Thriving: Our Real Fibromyalgia JourneyA conversation with Dr. Purser
YouTubeJun 19, 2026

From Bedridden to Thriving: Our Real Fibromyalgia Journey

🎉 June Anniversary Special at Purser Wellness! Join Dr. Dan Purser MD’s team — Chantel (Chicky), Denise Purser, and Lois Schweigert from End Fibro with Natural Options — for an honest, heartfelt conversation about living well with fibromyalgia. We share real-life stories of flares, recovery, and ongoing improvement using Dr. Purser’s protocol. From severe teenage fibromyalgia to thriving as grandmothers, we discuss how the VARS Trio (Glutathione, SOD, and the game-changing Catalase) helps manage inflammation, cytokines, and hydrogen peroxide — plus practical tips on low-copper diet, serving sizes, gym recovery, weight loss, and consistency over perfection. Topics covered: • How to handle fibro flares quickly (catalase + SOD stories) • The importance of intracellular testing (CMA) & genetics • Low-copper eating guidelines & why serving size matters • Building strength and muscle after years of pain • Why we keep improving year after year 🔥 June Special: $100 off Genetic Testing + CMA (deepest discount of the year). One lucky order will be fully reimbursed! 👉 Order tests & supplements: https://danpursermd.com (or link in comments) If you or someone you love deals with fibromyalgia, chronic pain, fatigue, or inflammation, this episode is full of hope and actionable advice. 💬 Drop your biggest takeaway or question below — we read every comment! Timestamps: 00:00 - Intro & June Anniversary Sale 02:30 - Real flare story & catalase rescue 06:00 - Long-term improvement on the protocol 12:00 - Starting slow with supplements (topical tips) 23:00 - Low-copper diet & food list tips 36:00 - Gym recovery & building muscle 50:00 - Weight loss benefits & consistency #Fibromyalgia #ChronicPain #NaturalWellness #PurserWellness #FibroRecovery #LowCopperDiet Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

CC Searchable captions
Pain & wellbeing
Purser Wellnessexplore

Good questions open new doors.

Dan Purser MD Physician Designed YouTube Substack Find My PathwayCoursesNutrients & foodsGenes & pathwaysBooks & chaptersAbout this library
© 2026 Purser Wellness

For education. The archive includes clinical perspectives and historical material; it does not replace individual medical care.

Sources & coverageAbout the teachingPrivacyContact & help
Purser Wellnessexplore
DiscoverTopicsCoursesWatchReadAsk Purser
My learning
If you have any methylation issues, you won’t process glutathione properly. Bad! — Purser Wellness Explore