Skip to content
Back to the library
YouTube·YouTube publication: Aug 9, 2025

High homocysteine isn’t just a lab number—it’s a warning sign.

InflammationGenetics
Open on YouTube
From the original video description

Original sourceDan Purser MD on YouTube

Read the conversation.

YouTube captions · Unreviewed · Imported 2026-09-22

Captions can mishear medical terms, names, and doses. Check the recording for context. Each timestamp opens that moment on YouTube.

9 timestamped passages

0:03

Homocyine is a very interesting molecule where it's needed in our body for an a pro-inflammatory response for certain times of life for certain things. But certain genes overactivate homocyine causing hyper homocyinemmia or way too

0:19

much homoyine to be created. What's interesting is homocyine is part of the transuleration pathway and the transuleration pathway parallels with the methylation pathway methylation cycle. And so both of these together, if

0:36

you have genetic errors in your methylation cycle such as MTHFR, MTR, MTRR, GGH and many others, this directly affects your homoyine production in the transforation pathway. So MTHFR

0:53

could be one of the top causes of strokes and kidney failure at the end of the day. One of the other major causes of homocyine, high homocyine are vitamin deficiencies caused by genetic errors in the methylation cycle. Exactly what I

1:09

was just saying, MTHFR, MTR, MTRR are all directly related to causing high homoyine levels. So knowing all this, what can you do? You have to address these deficiencies first. And that's

1:24

where we created MTHFR daily to fill these holes of many of these genetic errors. MTHFR daily is perfectly tuned to fill the methylation cycle and all those areas that are lacking. Along with that, you can utilize glutathione or

1:41

reduced glutathione like in vars glutathione. By using glutathione you can stabilize the downstream effects of hyperhomocyinemmia by reducing the amount of cytoines that are created because of the high homocyine levels. So bars glutathione

1:59

mthfr daily are two of your best chances of fighting hyperhomocyinemmia and lowering the inflammation and the pain that's caused by it. So definitely check out these products. Uh don't be scared. Uh there's a lot you can do to

2:15

help prevent these things and we're here to answer your questions all along the way.

PURSER WELLNESS · PRACTICE & SHOP

Explore your next step.

VARS Glutathione Capsules product packagingPHYSICIAN DESIGNEDVARS Glutathione CapsulesCapsule product informationView productVARS Liposomal Glutathione product packagingPHYSICIAN DESIGNEDVARS Liposomal GlutathioneLiquid product informationView productPHYSICIAN DESIGNEDMTHFR DailyProduct information & ingredientsView productTESTING & CONSULTATIONGenetic testing + consultationExplore the available testing bundlesExplore testing

Product and testing details from our practice and shop. Discuss what fits your needs with your clinician. Current labels, availability and pricing are shown on the linked pages.

ONE MORE CONNECTION MADE

Keep your curiosity going.

A LITTLE CLARITY

Understand the terms

Open a short reference guide.

Homocysteine and methylation→GGH→MTHFR→

FOLLOW YOUR CURIOSITY

Go deeper into this discussion

Homocysteine: follow the connections

Mentions homocysteine.

Inflammation topic
Methylation & B vitamins

Mentions methylation in the captions.

Genetics topicWatch at 0:19 ↗
Your MTHFR starting point

Mentions mthfr in the captions.

Genetics topicWatch at 0:36 ↗

Connections follow subject mentions. Read or watch the source for context.

FOLLOW THE THREAD

Inflammation & antioxidants

Follow the conversations on homocysteine, glutathione, antioxidant defenses, and redox balance.

Explore this topic
A note on the archive

These are the original author’s words and perspectives. Older material may reflect earlier teaching. Use the source and publication date for context.

MORE FROM PURSER WELLNESS

Genetic testing + consultationExplore your inherited patterns.
Physician DesignedMeet the products behind the teaching.
CMA testing + consultationExplore intracellular nutrient testing.

Keep following the thread.

More to explore

A term in this discussion

PURSER WELLNESSMTHFRFrom the reading room
Gene referenceSep 17, 2026

MTHFR

Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.

Genetics

A term in this discussion

PURSER WELLNESSMTRFrom the reading room
Gene referenceSep 17, 2026

MTR

Makes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.

Genetics

A term in this discussion

PURSER WELLNESSMTRRFrom the reading room
Gene referenceSep 17, 2026

MTRR

Helps maintain the activity of methionine synthase, connecting B12-related chemistry with homocysteine metabolism.

Genetics

A term in this discussion

PURSER WELLNESSHomocysteine and methylationFrom the reading room
Learning essentialsSep 17, 2026

Homocysteine and methylation

Learn the vocabulary before trying to interpret a pathway.

Testing
Purser Wellnessexplore

Good questions open new doors.

Dan Purser MD Physician Designed YouTube Substack Find My PathwayCoursesNutrients & foodsGenes & pathwaysBooks & chaptersAbout this library
© 2026 Purser Wellness

For education. The archive includes clinical perspectives and historical material; it does not replace individual medical care.

Sources & coverageAbout the teachingPrivacyContact & help
Purser Wellnessexplore
DiscoverTopicsCoursesWatchReadAsk Purser
My learning
High homocysteine isn’t just a lab number—it’s a warning sign. — Purser Wellness Explore