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Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.

Dr. Purser’s subscriber report on MAO-A, genetic terminology, and the anxiety-related questions discussed in the public introduction.

Dan and Jackson discuss methylated B vitamins, the term overmethylation, and questions to ask when your response to a supplement changes.

A conversation about GAD genes and GABA, with Dan Purser MD and Jackson Larkin.

A post from Purser Wellness on Substack, covering genetics and methylation, gut and digestion, mind, mood, and sleep.

A episode from Purser Wellness on Substack, covering mind, mood, and sleep.

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, mind, mood, and sleep.

PURSER WELLNESSUnderstanding Your CMA with Redox Results: What Those Two Pages Actually MeanA conversation with Dr. Purser

If you’ve had our Cellular Micronutrient Assay (CMA) with Redox testing, chances are you’ve looked at those two pages of results and thought, “Okay... now what does all this actually mean?” You’re not alone. This is one of the questions I hear most often from patients. Let me walk you through exactly what each page shows, how the test works, and why these results are so powerful for creating a truly personalized plan to help you feel your best.

How Broken Methylation, High Homocysteine, and Depleted Glutathione Are Driving the Rise Since the 1980s

A episode from Purser Wellness on Substack, covering mind, mood, and sleep.

From Brain Fog to Burnout: The Hidden Deficiencies Your Bloodwork Misses. By Dan Purser MD

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors MissFrom the reading room

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation. This is not fringe theory. It is the clinical reality I have