Let’s explore “oxidative stress”

This report overview covers NASH, liver cirrhosis, oxidative stress, and the treatment comparisons presented in the source report.

This report overview covers RAD50, the MRE11–RAD50–NBS1 (MRN) complex, DNA double-strand breaks, genomic stability, and the DNA-repair and oxidative-stress pathways discussed in the source.

PURSER WELLNESSWhat is VARS? Super Antioxidant Protection?A conversation with Dr. Purser

🔬 What is VARS? Why the VARS Trio (Glutathione + SOD + Catalase) is a game-changer for inflammation, recovery & fibromyalgia. Jackson Larkin sits down with Lois Schweiger to break down Dr. Dan Purser MD’s VARS line — Validated, Absorbable, Reduced, and Stable antioxidants. Learn the science behind VARS Glutathione, VARS SOD (from deep-sea algae near volcanic vents), and the newest VARS Catalase (Nrf2 activator from seaweed). Discover: • How the VARS Triad works together in the mitochondria to fight oxidative stress and cytokines • Why Catalase dramatically improved post-workout recovery (especially leg day!) • Genetics, homocysteine, PEMT, and why many with fibro benefit from this protocol • The importance of CMA (intracellular) testing and when to retest • Real patient results, including severe inflammation cases Perfect for anyone dealing with chronic pain, inflammation, slow recovery, or looking for root-cause support. **June Anniversary Special**: $100 off Genetic + CMA testing — one order will be fully reimbursed! 👉 Learn more & shop VARS supplements: danpursermd.com #VARSGlutathione #Fibromyalgia #Antioxidants #ChronicInflammation #PurserWellness #Catalase #SOD Timestamps: 00:00 Intro & What Does VARS Mean? 01:45 The Science of the VARS Triad 12:00 Who Needs the Trio? 14:00 Catalase & Workout Recovery Stories 20:00 Genetics, Homocysteine & Testing Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSVARS TRIAD | What Does That Mean? | Live with Dan Purser MDA conversation with Dr. Purser

Discover the power of the VARS Triad (also called the REDOX Triad)—Dr. Dan Purser MD’s groundbreaking, patented antioxidant protocol featuring VARS Glutathione, VARS SOD, and VARS Catalase. In this live session, Dr. Purser breaks down what VARS stands for (Validated, Absorbable, Reduced, Stable), how this physician-designed trio supports your body’s natural redox balance, quiets inflammation and cytokines at the root-cause level, and helps overcome genetic challenges like high homocysteine, oxidative stress, and related chronic issues. Perfect for anyone exploring advanced functional medicine and targeted supplementation. Learn more at https://physiciandesigned.com/blogs/glutathione/discover-the-vars-trio-your-bodys-ultimate-antioxidant-powerhouse

PURSER WELLNESSAutism Answered - Root Cause Solved with #1 Reviewed MD in the USAA conversation with Dr. Purser

Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

PURSER WELLNESSThe Real Problem With CT Scans?A conversation with Dr. Purser

While CT scans are sometimes necessary, the radiation exposure they create can cause oxidative damage in the body. That’s why antioxidants like glutathione are so important—when taken in a validated, reduced form, they help detox and protect against the harmful effects of scans, heavy metals, and chemicals like gadolinium. Dr. Purser’s VARS Glutathione and Nayan Patel’s topical Glutaryl formulas are the only patented, validated glutathiones proven to actually work at this level, helping patients recover quickly from oxidative stress.

PURSER WELLNESSDefeat Inflammation with Super Antioxidants?A conversation with Dr. Purser

Superoxide Dismutase 3 (SOD 3), also known as extracellular SOD or ubiquitous SOD, plays a critical role in your body’s defense against inflammation and oxidative stress. Here’s why it matters: Stabilizes Mast Cells SOD 3 helps suppress mast cell activation, reducing the release of inflammatory mediators that contribute to conditions like skin inflammation, inflammatory bowel disease, and chronic pain. Reduces Pro-Inflammatory Cytokines By inhibiting cytokines like TNF-Alpha, SOD 3 can help soothe inflammation at its source. Supports Healthy Joints and Blood Vessels Whether you have joint disc

PURSER WELLNESSFrom Fibromyalgia to Feeling FantasticA conversation with Dr. Purser

…l of that my mom passed away. There was a lot of, you know, stress and, you know, dealing with my dad. And so it makes sense when you look back on what was going on. I was just, my body was burning through everything. Yeah. Just trying to i…

PURSER WELLNESSUnable to Detox From Inflammation?A conversation with Dr. Purser

…e body it is the first and go-to first line defense against oxidative stress and oxidative damage within our cells within the mitochondria as well as throughout our blood vessels. Glutathione is ubiquitous. It's everywhere and our body util…

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

…disrupted—because of nutritional deficiencies, genetics, or oxidative stress—homocysteine begins to accumulate. Traditionally, the focus was on lowering the number itself. The Purser Model suggests something more important is happening. The…

…ith: Cardiovascular, Vascular function, Superoxide removal, Oxidative stress, Connective tissue. These are teaching connections, not a diagnosis or a measured effect in your body. Understanding a result A gene name is not a test result. Int…

… groups this subject with: Brain health, Neurodegeneration, Oxidative stress. These are teaching connections, not a diagnosis or a measured effect in your body. Understanding a result A gene name is not a test result. Interpretation needs t…