The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step
The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step
https://danpursermd.substack.com/p/can-glutathione-reverse-kidney-disease?utm_source=youtube
Chapter 32: Early Intervention in Chronic Kidney Disease- The Therapeutic Potential of VARS Glutathione for Cytokine Suppression and Renal Recovery
Glutathione and kidney disease: a proposed research direction
The idea to explore
A readin…
Struggling with inflammation, high cytokines, or conditions like psoriasis, kidney disease, or chronic fatigue? The root cause could be elevated interleukins like IL-8 and MCP-1, often triggered by high homocysteine levels. The most powerful natural solution we’ve found?
Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions.
For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered.
New research and clinical observations are changing that view.
We introduce a new framework called the Purser Model, which explains why homo
Discover the power of the VARS Triad (also called the REDOX Triad)—Dr. Dan Purser MD’s groundbreaking, patented antioxidant protocol featuring VARS Glutathione, VARS SOD, and VARS Catalase. In this live session, Dr. Purser breaks down what VARS stands for (Validated, Absorbable, Reduced, Stable), how this physician-designed trio supports your body’s natural redox balance, quiets inflammation and cytokines at the root-cause level, and helps overcome genetic challenges like high homocysteine, oxidative stress, and related chronic issues. Perfect for anyone exploring advanced functional medicine and targeted supplementation.
Learn more at https://physiciandesigned.com/blogs/glutathione/discover-the-vars-trio-your-bodys-ultimate-antioxidant-powerhouse
Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum.
It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges.
The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal.
This isn’t theory. It’s the Purser Method® in action.
If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.
In this powerful live session, Dr. Dan Purser MD reveals why conventional pediatric medicine often falls short and shares his proven Purser Method® for helping children with autism spectrum traits, severe ADHD, chronic inflammation, and developmental delays.
Drawing from over 43 years of clinical experience, Dr. Purser explains:
Why genetic testing (especially MTHFR and related SNPs) is the essential first step
How to use targeted, active-form nutrients instead of generic vitamins
The role of leucovorin (high-dose folinic acid) and when it makes a real difference
Practical ways to reduce toxin load and calm the inflammatory response
Smart strategies around vaccination and detoxification support
Dr. Purser emphasizes that kids are not little adults — their developing systems need precise, individualized care. Parents and practitioners will walk away with actionable steps that address root causes rather than just managing symptoms.
Whether your child is struggling with speech delays, meltdowns, focus issues, or recurrent health problems, this episode offers real hope through biochemistry done right.
Resources Mentioned:
Pediatric MTHFR formulas: https://www.PhysicianDesigned.com
Book a consultation: http://www.DanPurserMD.com
Dr. Purser’s books on Amazon: https://www.amazon.com/-/e/B00BIKSGVQ
If you’re a parent tired of “there’s nothing more we can do,” or a practitioner looking for better tools, this episode is for you.
Timestamps available in the full video.
Subscribe, leave a review, and share this with any parent who needs to hear it. The kids deserve better answers.
Dan Purser MD – Root Cause Inflammation & Genetic Optimization
#MTHFR #Autism #ADHD #ChildrensHealth #Leucovorin #FunctionalMedicine #Pediatrics
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Info: http://www.DanPurserMD.com
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…ay about the patient, but he had significant cardiovascular disease, which was surprising. I've seen several cases like this um over the years obviously because of homoyine, but um he had interesting findings. He had a um a double homozygou…
…ay about the patient, but he had significant cardiovascular disease, which was surprising. I've seen several cases like this um over the years obviously because of homoyine, but um he had interesting findings. He had a um a double homozygou…
…re earlier tonight about dementia, Alzheimer's, Alzheimer's disease, how common it is. I don't think it's that common. I think what we're seeing is a lot of patients with vitamin deficiency. You get a ri you get a a B1 or thyon deficiency. …
…re earlier tonight about dementia, Alzheimer's, Alzheimer's disease, how common it is. I don't think it's that common. I think what we're seeing is a lot of patients with vitamin deficiency. You get a ri you get a a B1 or thyon deficiency. …
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