Let’s explore “Homocysteine and methylation”

Learn the vocabulary before trying to interpret a pathway.

Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.

This report overview covers the author’s homocysteine teaching notes on transsulfuration, methylation, glutathione, genetic variants, cytokines, and the connections proposed in the collection.

Dr. Purser shares his clinical perspective on homocysteine, methylation, and inflammatory patterns.

PURSER WELLNESSHigh Homocysteine, MTHFR Mutations, and the Inflammation Crisis: The Cardiovascular, Fertility, andA conversation with Dr. Purser

How Elevated Homocysteine, Impaired Methylation, and Glutathione Deficiency May Be Driving PCOS, Chronic Pain, Brain Fog, Stroke Risk, and Detox Failure — and Why Genetic Testing WILL Change the Way https://danpursermd.substack.com/p/high-homocysteine-mthfr-mutations?utm_source=youtube

PURSER WELLNESSWhy does MTHFR correlate with high homocysteine?A conversation with Dr. Purser

Follow Dr. Purser! Did you know your MTHFR gene can impact your homocysteine levels? High homocysteine is linked to heart and brain health—understanding this connection could be the key to solving your mystery medical problems that no doctor or study has been able to figure out. Curious how it all works? Let’s break it down in simple terms. #insulin #genetics #vitamins #Vars #wellness #PEMT #inflammation #glutathione #MicronutrientTesting #FunctionalMedicine #SOD #Homocysteine #ChronicInflammation #MethylationMatters #FunctionalWellness #GeneticTesting #NutrientDeficiency #MTHFR #fibromyalgia #Methylation #DrDanPurser #purserwellness Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Most chronic inflammation, gut issues, and detox problems aren’t aging or bad luck — they’re methylation disorders your doctor probably ignores. MTHFR and homocysteine matter more than mainstream medicine admits, and the research is about t

A post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

A post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

A subscriber post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

PURSER WELLNESSCope with Homocysteine Like a Pro!A conversation with Dr. Purser

High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even infertility. Genetics play a big role—there are 17 SNPs that can lock homocysteine in place—but vitamin deficiencies can make it worse. The real breakthrough isn’t lowering homocysteine itself but calming the cytokines it triggers, like IL-8 and MCP-1. That’s why VARS Glutathione, the only patented oral form proven to work, is so powerful—it lowers those cy

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho