CCL4 encodes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines.
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What’s searchable?Explore macrophage inflammatory protein-1 beta, CCR5, T cells, natural killer cells, and monocytes.
CCL3 encodes MIP-1 alpha, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct.
…r. Purser connects chemokines such as IL-8, CCL2/MCP-1, and CCL4 with Th1/Th17 signaling and cytokines including TNF-alpha, IL-6, and IL-1 beta. He discusses the interaction of immune-cell recruitment and tissue injury. Bring these questio…
…mmation and allergic contexts. Its relationship to CCL3 and CCL4 helps explain why several recruitment signals can overlap during an inflammatory episode. A CCL5 marker cannot identify the trigger on its own. A question to bring to your vis…
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