IL12B
Some search terms matchedIL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine.
Also called:
A shared component of two cytokines
IL12B encodes the p40 subuni…
IL13
Some search terms matchedIL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal.
Also called:
Allergic signaling and tissue responses
…
IL15
Some search terms matchedIL15 encodes a cytokine involved in the survival and activity of immune cells, including natural killer cells and memory CD8 T cells. Its receptor system includes IL15RA.
Also called:
Supporting immune-cell survival
IL15 encodes a cytokine…
IL15RA
Some search terms matchedIL15RA encodes the alpha receptor component for IL-15. It helps present IL-15 to responding immune cells, supporting communication that is important for particular lymphocyte populations.
Also called:
Presenting IL-15 to responding cells
I…
IL17A
Some search terms matchedIL17A encodes interleukin-17A, a cytokine involved in defense at tissue barriers and inflammatory signaling. It belongs to the Th17 pathway, which is supported by signals including IL-23.
Also called:
Th17 signaling and persistent inflamma…
IL18R1
Some search terms matchedIL18R1 encodes a component of the receptor for IL-18. It works with an accessory component, IL18RAP, to support IL-18 signaling.
Also called:
The binding side of the IL-18 receptor
IL18R1 encodes a component of the receptor for IL-18. It w…
IL18RAP
Some search terms matchedIL18RAP encodes an accessory protein in the IL-18 receptor complex. The receptor needs coordinated components to translate an extracellular signal into a cellular response.
Also called:
The accessory component of IL-18 signaling
IL18RAP en…
IL1B
Some search terms matchedIL1B encodes interleukin-1 beta, a cytokine involved in inflammatory responses and fever. Its production and activation are regulated processes, not simply an on/off consequence of having a common SNP.
Also called:
IL-1β and the early infl…
IL22
Some search terms matchedIL22 encodes a cytokine that acts on tissues such as epithelial barriers. It can support barrier defense and repair, while its effects depend on the tissue and inflammatory setting.
Also called:
Barrier defense, repair and excess tissue gr…
IL23A
Some search terms matchedIL23A encodes the p19 subunit of interleukin-23. Together with the p40 subunit encoded by IL12B, it forms a cytokine involved in supporting Th17 responses.
Also called:
The p19 component of IL-23
IL23A encodes the p19 subunit of interleuki…
IL2RA
Some search terms matchedIL2RA encodes the alpha chain of the interleukin-2 receptor, also called CD25. It is involved in immune activation and regulatory T-cell biology; a soluble receptor measurement is distinct from a DNA result.
Also called:
CD25 and immune-ce…
IL33
Some search terms matchedIL33 encodes interleukin-33, a signal that can act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells.
Also called:
An alarmin in allergic s…
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