THE PURSER WELLNESS LIBRARY

Let’s explore chronic fatigue

A COURSE FOR YOUR CURIOSITYFatigue: asking better questions

4 chapters, at your pace

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New to this subject? Start with this free introduction.What Causes Chronic Fatigue Syndrome?

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YouTubeAug 29, 2026

MTHFR and the Never-Ending Sugar Crash Cycle: Why You’re Tired, Craving Sugar, and Chasing Energy A

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That afternoon sugar craving may be telling you more than you think. Here’s how methylation, glucose, cellular energy and your genetics may fit into the bigger picture. https://danpursermd.substack.com/p/mthfr-and-the-never-ending-sugar?utm_source=youtube

YouTubeJan 6, 2026

What is MTHFR? What can YOU do about it?

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MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

YouTubeJan 6, 2026

What Happens If You Have A Gene SNP?

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Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

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