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…ions to your visit Ask which organs need monitoring and how disease activity will be controlled. Breathing difficulty, voice changes, or hearing problems warrant prompt assessment.

Dr. Purser discusses interleukins and oxidative stress in cystic fibrosis lung disease.

NOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease.

PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.

F9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.

Explore migraine, neurovascular inflammation, trigeminal signaling, CGRP, and related research.

…ity is being monitored and what benefits and risks apply to disease-modifying treatment. Antioxidant or nutrient discussions do not establish reversal of demyelination or replace the treatment plan.

Homocysteine rarely gets the attention of cholesterol, blood sugar, or blood pressure. It should. When homocysteine becomes elevated, it has been associated with cardiovascular disease, stroke, cognitive decline, blood clots, and other he

Explore interleukin-6, C-reactive protein (CRP), the acute-phase response, rheumatoid arthritis, and related health conditions.

By Dan Purser MD Pathway-level clinical interpretation focused on inflammatory interaction, likely signs, and likely complications

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, genetics and methylation.