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Everyone talks about MTHFR. But what if that is only one piece of the puzzle? MTHFR helps process folate, while MTR helps recycle homocysteine back into methionine with the help of vitamin B12. Two genes. Different roles. One interco

BHMT helps recycle homocysteine into methionine using betaine. It is a different route from the folate and B12 pathway.

The homocysteine chapters include MTHFD1L in the wider folate-related genetic map.

Explore rs2236225, rs1076991, folate-dependent one-carbon metabolism, nucleotide synthesis, homocysteine, and double homozygosity.

Explore SERPINE1 / PAI-1, rs1799889, 4G/5G, fibrinolysis, hyperhomocysteinemia (HHcy), vascular health, and differences between approaches to clotting risk.

Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.

Discover the glutathione and homocysteine connection and learn why personalized testing may provide valuable information to discuss with your healthcare professional. Find out more and discover the wellness help you have been looking for a

Explore transsulfuration, methylation, glutathione, genetic variants, cytokines, and possible connections.

What if your homocysteine level is telling you more than you realize? When kidney function declines, homocysteine levels often rise because the kidneys play an important role in its metabolism and clearance. In people with chronic kidney d

Why are so few people talking about homocysteine when discussing autism? While conversations around autism often focus on behaviors and symptoms, some researchers and wellness professionals have explored whether underlying biochemical fact

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, mind, mood, and sleep.