THE PURSER WELLNESS LIBRARY

Let’s explore 1,25-dihydroxyvitamin D — lab reference

A COURSE FOR YOUR CURIOSITYGetting to know your micronutrients

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Gene referenceSep 23, 2026

CD40LG

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CD40LG encodes CD40 ligand, which binds CD40 and supports communication needed for effective antibody responses. It is on the X chromosome, which changes how some genetic results must be interpreted. Also called: The ligand that helps acti…

Gene referenceSep 23, 2026

CETP

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…poprotein particles. This helps explain why the balance of HDL and other lipid particles is more complex than a single cholesterol number. Also called: Moving cholesterol between lipoproteins CETP transfers cholesteryl esters between lipop…

Gene referenceSep 23, 2026

CXCL13

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CXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings. Also called: Guiding B cells to organized immune sit…

Gene referenceSep 23, 2026

CXCL8

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CXCL8 is the gene for IL-8, a chemokine involved in recruiting and activating neutrophils. IL-8 is the protein nickname; CXCL8 is the gene name a DNA report may use. Also called: IL-8: bringing neutrophils to the response CXCL8 is the gene…

Gene referenceSep 23, 2026

CXCR5

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CXCR5 encodes the receptor for CXCL13. This receptor helps guide B cells and certain T cells toward locations where organized immune responses develop. Also called: Following the CXCL13 signal CXCR5 encodes the receptor for CXCL13. This re…

Gene referenceSep 23, 2026

F5

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F5 encodes coagulation factor V. The well-characterized Factor V Leiden variant, rs6025, can make factor V less responsive to an anticoagulant control mechanism, increasing susceptibility to venous clots. It does not mean the body cannot ma…

Gene referenceSep 23, 2026

F9

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F9 encodes coagulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding. Also called: Factor IX and the bleeding sid…

Gene referenceSep 23, 2026

GSTO2

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GSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1. Also called: A distinct member of the …

Gene referenceSep 23, 2026

IFNG

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IFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses. Also called: Interferon gamma and macrophage activati…

Gene referenceSep 23, 2026

IL10

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IL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one. Also called: The immune system al…

Gene referenceSep 23, 2026

IL12B

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IL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine. Also called: A shared component of two cytokines IL12B encodes the p40 subuni…

Gene referenceSep 23, 2026

IL13

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IL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal. Also called: Allergic signaling and tissue responses …

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