DDAH1
Some search terms matchedDDAH1 encodes an enzyme that breaks down asymmetric dimethylarginine, or ADMA. ADMA inhibits nitric oxide synthase; DDAH1 is part of its clearance system, not the inhibitor itself.
Also called:
Clearing ADMA helps preserve nitric oxide sig…
F5
Some search terms matched…The well-characterized Factor V Leiden variant, rs6025, can make factor V less responsive to an anticoagulant control mechanism, increasing susceptibility to venous clots. It does not mean the body cannot make factor V.
Also called:
Factor…
F9
Some search terms matched…ulation factor IX. Disease-causing variants can result in hemophilia B, an inherited bleeding disorder, but a panel marker is not equivalent to a confirmed disease-causing finding.
Also called:
Factor IX and the bleeding side of coagulatio…
GSTO2
Some search terms matchedGSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1.
Also called:
A distinct member of the …
HMGB1
Some search terms matchedHMGB1 normally has functions inside the cell nucleus. When released outside cells in particular settings, it can act as a damage-associated molecular pattern, or DAMP, participating in inflammatory signaling.
Also called:
A cellular protei…
IFNG
Some search terms matchedIFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses.
Also called:
Interferon gamma and macrophage activati…
IL10
Some search terms matchedIL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one.
Also called:
The immune system al…
IL12B
Some search terms matched…12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine.
Also called:
A shared component of two cytokines
IL12B encodes the p40 subunit …
IL13
Some search terms matchedIL13 encodes interleukin-13, a cytokine involved in Th2 immune responses, mucus-related processes and tissue remodeling. It overlaps with some IL-4 functions but is not the same signal.
Also called:
Allergic signaling and tissue responses
…
IL15
Some search terms matched…ncodes a cytokine involved in the survival and activity of immune cells, including natural killer cells and memory CD8 T cells. Its receptor system includes IL15RA.
Also called:
Supporting immune-cell survival
IL15 encodes a cytokine invol…
IL15RA
Some search terms matchedIL15RA encodes the alpha receptor component for IL-15. It helps present IL-15 to responding immune cells, supporting communication that is important for particular lymphocyte populations.
Also called:
Presenting IL-15 to responding cells
I…
IL16
Some search terms matched…ukin-16, a cytokine involved in attracting and influencing immune cells, including CD4-expressing cells. Its recruitment role helps separate it from other numbered interleukins.
Also called:
A cytokine involved in immune-cell traffic
IL16 …
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