THE PURSER WELLNESS LIBRARY

Let’s explore Homocysteine and methylation

A COURSE FOR YOUR CURIOSITYYour MTHFR starting point

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199 discoveries for your curiosity13 matching listings grouped; alternative sources stay available.

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Gene referenceSep 17, 2026

AHCY

In the article

…he Purser reference The reference groups this subject with: Homocysteine metabolism, Methylation, Methionine processing, Homocysteine regulation, Transsulfuration. These are teaching connections, not a diagnosis or a measured effect in your…

Gene referenceSep 17, 2026

FOLH1

In the article

… The reference groups this subject with: Folate absorption, Homocysteine regulation, Glutamate signaling, Methylation, Folate metabolism, Transsulfuration, PCOS, Insulin/glucose regulation, Hormone metabolism. These are teaching connections…

Gene referenceSep 17, 2026

MTHFD1

In the article

… The reference groups this subject with: Folate metabolism, Homocysteine regulation, Transsulfuration, Methylation. These are teaching connections, not a diagnosis or a measured effect in your body. Understanding a result A gene name is not…

FacebookAug 31, 2026

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health.

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MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status

YouTubeAug 6, 2026

OVER-METHYLATION - Are Your B Vitamins Hurting You?

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Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

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