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…ne to methionine. A severe deficiency can affect blood-cell production and other body systems. Follow the pathway Dr. Purser connects folate with SLC19A1 transport, MTHFR and MTHFD1 metabolism, B12, and homocysteine. He discusses anemia, f…

…also support the betaine/BHMT route and phosphatidylcholine production. Bring these questions to your visit Ask whether folate, B12, homocysteine, choline intake, and liver findings help put the genetic result in context. Two identical all…

…elling us? Understanding your homocysteine level, nutrient status, lifestyle, and genetics together will provide valuable information to discuss with a knowledgeable healthcare professional. Test. Understand. Ask better questions. T…

…d system involving glucose metabolism, mitochondrial energy production, nutrients, sleep, stress, and genetics. MTHFR is one major piece of that bigger picture. Variants such as C677T and A1298C can influence folate metabolism and methyla…

…ects this navigation system with germinal centers, antibody production, and immune regulation. The name of a receptor on a panel is different from a measurement of how strongly the entire pathway is operating. Bring these questions to your…

…thylarginine, or ADMA. ADMA can interfere with nitric oxide production, which matters for the normal relaxation of blood vessels. Follow the pathway Dr. Purser follows ADMA, nitric oxide synthase, endothelial function, and oxidative stress…

…4 T/A variant, is discussed in research on interferon-gamma production. The same gene can have many variants with different meanings. Follow the pathway Dr. Purser follows IFN-γ signaling into T-cell and macrophage activity and the relatio…

…13 participates in type 2 immune signaling, including mucus production, allergic inflammation, and changes in barrier tissues. It works closely with IL-4 but is a distinct signal. Follow the pathway Dr. Purser connects IL-13 with eosinophi…

…ssic signaling, trans-signaling, JAK/STAT3, and the liver’s production of C-reactive protein. He also connects homocysteine and oxidative stress with inflammatory activity. IL6 and IL6R are different genes; a variant in either is not equiva…

…ollows TLR2 signaling through MyD88 and NF-κB into cytokine production. This connects the initial recognition of a trigger with inflammation, blood-vessel and joint research, and the antioxidant network. Bring these questions to your visit…

…ioxidants every single day. Yet understanding nutritional status can be more complicated than simply looking at a standard lab panel. A CMA is designed to provide another perspective on how your cells respond to essential nutrients, givi…

… about is PEMT. PEMT plays an important role in the body's production of phosphatidylcholine, which is involved in transporting fat out of the liver. Certain genetic variations may influence this pathway and can affect individual choline r…