Let’s explore “cardiovascular risk”

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors MissFrom the reading room

…ion of inflammatory cytokines. Homocysteine is not merely a cardiovascular marker. It is a potent “cytokine amplifier.” When levels climb above 10–12 µmol/L (my functional optimum is <7–8 µmol/L), homocysteine directly stimulates production…

PURSER WELLNESSA Natural Approach to Lowering High Blood PressureFrom the reading room

…die from heart disease than breast cancer. Among women, the risk of having a heart attack greatly increases during the 10 years after menopause 1 in every 5 female deaths in the US is attributed to heart disease. Approximately 1 in every 16…

…dicine. Follow the connections The fourteen chapters cover cardiovascular disease, immune function and cancer, stroke, pulmonary disease, accidents, diabetes, pneumonia and influenza, dementia, end-stage kidney disease, septicemia, hormone…

…rd its numerical targets or treatment checklists. Think in risks rather than guarantees The men’s prevention handbook groups topics by major health conditions, but prevention changes probabilities rather than guaranteeing a particular life…

…. Keep symptom relief separate from claims about preventing cardiovascular disease. Reading with perspective This 2015 report is historical teaching. Its treatment targets and assertions about cardiovascular protection are not reproduced a…

…lp organize a conversation about eligibility and individual risk. The history shapes the hormone discussion The HRT document highlights timing after menopause, blood pressure, clotting history, Factor V Leiden and cancer history. These are…

Dr. Purser’s subscriber report on PAI-1 4G/5G, homocysteine, and brain infarct risk. Read the report on Substack.

Encodes a protein involved in transporting fats. Some variants affect risk estimates, but they do not determine whether an individual will develop a disease.

This report overview covers SERPINE1 / PAI-1, rs1799889, 4G/5G, fibrinolysis, hyperhomocysteinemia (HHcy), vascular health, and the report’s comparisons of approaches to clotting risk.

This report overview covers dimethylarginine dimethylaminohydrolase 1 (DDAH1), asymmetric dimethylarginine (ADMA), nitric oxide, blood vessels, and the cardiovascular pathways discussed in the source.

This report overview covers the source’s discussion of rs1801406, BRCA2, DNA repair, cancer-risk interpretation, genetic counseling, and inflammatory signaling; the overview does not establish a variant’s classification or personal cancer risk.

PURSER WELLNESSGENETIC MUTATION DETECTION AND WHAT THAT MEANS for YOUA conversation with Dr. Purser

CRISPR is in the process of coming up with a treatment to change your genetic mutations. This could mean helping fix the mutations that put you at risk for Alzheimer's disease, macular degeneration, strokes, or Factor V Leiden. Stay on the look out for this very exciting new technology as it advances!