What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.
Dr.
Also called: Cystathionine Beta-Synthase
From homocysteine toward glutathione
Dr. Purser places CBS in the sulfur-handling pathway that connects homocysteine with glutathione production. In that map, CBS concerns the first step moving h…
Dr.
Also called: Cystathionine Gamma-Lyase
From homocysteine toward glutathione
Dr. Purser places CTH in the sulfur-handling pathway that connects homocysteine with glutathione production. In that map, CTH concerns the downstream step that …
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
What’s transsulfuration? It’s your body’s way of turning inflammatory homocysteine into glutathione, your master antioxidant. 🧬 If your glutathione is low, this pathway (often tied to CBS SNPs) might not be working—and it depends heavily on
Homocysteine is essential for the transsulfuration pathway and glutathione production. However, when levels get too high, it becomes harmful and hard to reduce. Mutations in the MTR and MTRR genes can further elevate homocysteine levels, ma
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