Let’s explore “DNA replication”

RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene.

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This report overview covers the source’s discussion of rs1801406, BRCA2, DNA repair, cancer-risk interpretation, genetic counseling, and inflammatory signaling; the overview does not establish a variant’s classification or personal cancer risk.

PURSER WELLNESSMTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving SweetsA conversation with Dr. Purser

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

You eat healthy. You take the supplements. Your labs look “normal.” So why do you still feel exhausted, anxious, foggy, or run down? What if the problem isn’t what you’re taking — but how your genes process it? Your DNA may influence how

PURSER WELLNESSWhat Happens If You Have A Gene SNP?A conversation with Dr. Purser

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

PURSER WELLNESS🧬 What’s more powerful than glutathione or vitamin C?A conversation with Dr. Purser

Superoxide dismutase (SOD)—your body’s first line of defense against DNA-damaging free radicals. SOD neutralizes superoxide radicals at the source of cellular energy production. But as we age—or if we have genetic SNPs—our ability to make SOD drops. That’s why we created VARS SOD, with over 10,000 IU per dose (most products have less than 240 IU). It’s a game changer for anti-aging, DNA protection, and reducing inflammation at the root.

Let’s Talk About MTHFR — The Gene That Impacts Your Energy If you’re constantly tired no matter how much you rest, your MTHFR gene may be part of the reason. MTHFR (Methylenetetrahydrofolate Reductase) is a genetic SNP—a small DNA variation

🧬 What’s more powerful than glutathione or vitamin C? Superoxide dismutase (SOD)—your body’s first line of defense against DNA-damaging free radicals. SOD neutralizes superoxide radicals at the source of cellular energy production. But as

Why did we get three different types of SOD? Because our bodies need targeted antioxidant defense—SOD1 protects nerves, SOD2 shields mitochondria and DNA, and SOD3 fights widespread inflammation. 🔬 If you’re low in any of them (especially a

The most potent antioxidant? Quite possibly, definitely one of the most incredible ones. SOD or superoxide dismutase is a critical antioxidant enzyme for the protection of your DNA, mitochondria, and cells. It is the baseline protection a

Could an antioxidant really stop your inflammation? Yes. And the molecular level, SOD, glutathione, and others remove inflammatory molecules and protect your cells and DNA from damage. This can have overall protective benefits all over your