Sex hormone-binding globulin (SHBG) — lab reference
Some search terms matchedEstrogen, thyroid, liver disease, insulin resistance, age, and medications affect SHBG.
THE PURSER WELLNESS LIBRARY
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What’s searchable?Estrogen, thyroid, liver disease, insulin resistance, age, and medications affect SHBG.
Female cycle-phase detail is on the next section. LC-MS/MS is preferred at low concentrations.
Female phase detail is on the next section. Exogenous progesterone route/timing matters.
Stress, sleep, nipple stimulation, medications, pregnancy, and macroprolactin matter.
M 18-30: 105-728; F 18-30: 83-377. Values decline substantially with age.
Assay-specific and age-dependent.
Method and units vary. Define clinical use before adopting a clinic target.
Assay-specific, especially at low concentrations.
No broadly accepted wellness target. Use exact assay and clinical indication.
Interpret with cycle timing and ovulation status.
Method-dependent; LC-MS/MS is preferred at very low values.
Wide physiologic variation.
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