Lab references

Reproductive and Sex Hormones

Sex hormone-binding globulin (SHBG) — lab reference

Estrogen, thyroid, liver disease, insulin resistance, age, and medications affect SHBG.

Updated Sep 23, 2026 · Educational reference

Purser Wellness approved rule

Unit: nmol/L

Male: 13.3-89.5

Female: 18-46 y: 18.2-135.5; ≥47 y: 16.8-125.2

How to read this marker

Estrogen, thyroid, liver disease, insulin resistance, age, and medications affect SHBG.

The wider testing context

Most sex-hormone values require age, collection time, cycle phase, menopausal status, pregnancy status, assay method, and exogenous hormone context.

Using this reference

This is the approved adult, nonpregnant baseline unless the rule explicitly states otherwise. Keep the performing laboratory’s reference interval separate from this Purser Wellness rule. Match units and review the specimen, method, timing, medicines and relevant clinical context before interpreting a result. These pages do not calculate a personal high/low status or prescribe treatment.

A question to bring to your visit

Which parts of the Sex hormone-binding globulin (SHBG) rule apply to my report’s method, units and collection conditions, and what other findings should we review alongside it?

Approved by Dr. Daniel Purser, MD · PW-LABS-1.0. The source laboratory’s interval remains separate.

Names you may see

Sex hormone-binding globulin (SHBG) · SHBG · Sex hormone-binding globulin