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A post from Purser Wellness on Substack, covering testing and nutrients.

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

Dr. Dan Purser literally writes out what glutathione is, why it is important to your body and your cells, and the difference between the useless oxidized version of glutathione (GSSG) and the functional version of glutathione (GSH). Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

CMA Consult Bundle and Genetic Consult Bundles are NOW ON SALE! Now through the first of December, take up to $100 off your testing bundles with me or my staff! Reach to my office to order the test and schedule. Info@danpursermd.com or 80

Common nutrient deficiencies linked to fibro often include copper, zinc, glutathione, B6, glutamine, B12, folate, molybdenum, and boron. When it comes to muscle cramping and fibro, magnesium is one of the most frequent deficiencies seen, of

When Justace first had CMA testing done, Dr. Purser told him he was malnourished—even though he was a young athlete eating constantly. The results showed real deficiencies that explained why he struggled to gain and maintain weight. After f

Dr. Purser and Justace discuss how genetics often reveal two major patterns in patients: either serious gut and liver issues like SIBO, pancreatitis, or colitis, or inflammatory problems tied to homocysteine and PEMT mutations. Sometimes pa

Patients often ask if they should stop supplements before an intracellular CMA test, and the answer is no. The test measures nutrient status inside your cells over the last 90–100 days, so stopping vitamins right before won’t change the results. At most, you might skip your dose a few hours before the draw, but it’s not necessary—CMA still provides an accurate snapshot of your nutrient levels while you’re on your current routine. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

CMA testing shows the vitamin deficiencies happening inside your cells, while genetic testing reveals why they’re happening in the first place. Patients often find their symptoms match exactly what the CMA shows, and when paired with genetic results, the root causes become clear. In most cases, it’s the genetic errors that drive the deficiencies—not the other way around—making the combination of both tests powerful for finding lasting solutions. DanPurserMD.com for all testing options or reach to my office! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

A post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

Why SNPs Matter for Your Health