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Dr. Purser explores questions about primary ovarian insufficiency (POI) and cytokines. The full subscriber post is on Substack.

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, hormones.

A subscriber post from Purser Wellness on Substack, covering inflammation and antioxidants, hormones, testing and nutrients.

A subscriber post from Purser Wellness on Substack, covering hormones, testing and nutrients.

A episode from Purser Wellness on Substack, covering hormones.

(And Why So Many Are Getting It Wrong)

Why Estradiol, Timing, and Physiology Matter More Than Fear

A episode from Purser Wellness on Substack, covering hormones.

PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors MissFrom the reading room

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation. This is not fringe theory. It is the clinical reality I have

PURSER WELLNESSCoQ10 and Thyroid MedicationA conversation with Dr. Purser

CoQ10 is an important nutrient that improves hypothyroidism and metabolism naturally. Explore how CoQ10 can help you with your energy levels and feel younger!

PURSER WELLNESSThe Hidden Molecule Driving Inflammation: Understanding the Purser Model of HomocysteineFrom the reading room

Most people have never heard of homocysteine, yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model, which explains why homo

The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step