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If you have a COMT mutation, your body may not break down estrogen or absorb B12 properly. 😵‍💫 The fix? Add DIM (like DIM Avail) for estrogen balance and use adenosyl + hydroxy B12 for better absorption. Start with drops or go straight to c

Can you take bioidentocal hormone replacement therapy if you have COMT?? Some say no, and they are wrong. You HAVE to use bioidential hormones and you HAVE to use someone that knows what they’re doing for treatment. If not, you may have p

Well, let’s talk about how to deal with your MTHFR. Methylation of folate is your key problem here. Not processing folate correctly leads to CHRONIC FATIGUE, never being able to make enough ATP. This is why you’re tired all the time, why

Let’s take a Quick Look at COMT, what it is, and how it affects patients. Is it linked to MTHFR? You betcha One of the base options for dealing with COMT is adenosyl/hydroxycobalamin, this mixture to two versions of B12 to support these

MTHFR, MTRR, MTR, ACHY, and COMT. These are the big 5 genetic SNPs that Gary Brecka and team look at. Its a great start but there are SO MANY more genes to look at to get the full picture. PEMT, GAD, SOD, NAT to name just a couple more. Y

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

This week Dr. Purser introduces his updated version of MTHFR Support Plus - now called MTHFR Endure. Order now at PhysicianDesigned.com. Dr. Purser goes on to discuss the various MTHFR genetic transcription errors, symptoms and ways to treat them. He also covers other top genetic errors that he sees and treats in his practice. If you have fibromyalgia, you most likely have MTHFR errors as well. How does MTHFR connect with COMT errors? Contact us at or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

Homocysteine - a very difficult molecule to keep in balance if you have genetic errors that affect your methylation and transsulfuration pathway. What does that even mean? You aren’t processing glutathione correctly but you can mitigate its

What are the basica of MTHFR, how did you get it, what can you do about it? We Dive Deep into the intricacies of MTHFR and methylation issues. Why are you tired all the time? Why are you so low energy? Because you aren’t processing yo

What are the basics of MTHFR, how did you get it, what can you do about it? We Dive Deep into the intricacies of MTHFR and methylation issues. Why are you tired all the time? Why are you so low energy? Because you aren’t processing your cri

Iron deficiencies, especiallly the ones that occur deep within your cells. What causes them? To understand why you’re not processing Iron, you have to view the key B Vitamins that help your body utilize Iron. The best way to check on these