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💡 Are You Aware of Your Homocysteine Levels? 💡Six key SNPs can cause dangerously high, fixed homocysteine levels. It’s crucial to understand this, especially if any of these SNPs are homozygous. If left unchecked, they can lead to serious h

Two bad SNPs to keep an eye on to protect against Brain Inflammation: NRTK2 and NRC31. These both cause a lower production of phosphatidylserine, a critical component for cellular structure, especially in the brain. If you need help getting

Every PCOS case I’ve seem over recent years has had BAD methylation genes from MTHFR SNPs. Get to the root and work up from there, and watch all thr symptoms get better. PCOS affects FAR TOO MANY women, but it doesn’t mean there are no opti

MTHFR, Methylation, and Beyond. Gary Brecka starts with just 5 SNPs, which is a great START! But its expensive and barely scratching the surface. Lets dive a little deeper and delve into these topics. NAFLD or fatty liver disease can be con

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine storms. That’s why VARS Glutathione is such a breakthrough: it’s reduced, functional, and proven to lower harmful cytokines like IL-8 and MCP-1, giving your body the detox power it needs. After 15 years of research and real patient results, it’s the only oral glutathione that actually works where it matters—inside your cells.

Coming soon: the DRP Genetic Cytokine Panel. This panel looks at 90 different cytokine gene SNPs. If even one of those SNPs is homozygous, it can drive major inflammatory issues that never fully settle with standard care. If you have unex

Coming soon: the DRP Genetic Cytokine Panel. This panel looks at 90 different cytokine gene SNPs. If even one of those SNPs is homozygous, it can drive major inflammatory issues that never fully settle with standard care. If you have unex

Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

In this powerful live session, Dr. Dan Purser MD reveals why conventional pediatric medicine often falls short and shares his proven Purser Method® for helping children with autism spectrum traits, severe ADHD, chronic inflammation, and developmental delays. Drawing from over 43 years of clinical experience, Dr. Purser explains: Why genetic testing (especially MTHFR and related SNPs) is the essential first step How to use targeted, active-form nutrients instead of generic vitamins The role of leucovorin (high-dose folinic acid) and when it makes a real difference Practical ways to reduce toxin load and calm the inflammatory response Smart strategies around vaccination and detoxification support Dr. Purser emphasizes that kids are not little adults — their developing systems need precise, individualized care. Parents and practitioners will walk away with actionable steps that address root causes rather than just managing symptoms. Whether your child is struggling with speech delays, meltdowns, focus issues, or recurrent health problems, this episode offers real hope through biochemistry done right. Resources Mentioned: Pediatric MTHFR formulas: https://www.PhysicianDesigned.com Book a consultation: http://www.DanPurserMD.com Dr. Purser’s books on Amazon: https://www.amazon.com/-/e/B00BIKSGVQ If you’re a parent tired of “there’s nothing more we can do,” or a practitioner looking for better tools, this episode is for you. Timestamps available in the full video. Subscribe, leave a review, and share this with any parent who needs to hear it. The kids deserve better answers. Dan Purser MD – Root Cause Inflammation & Genetic Optimization #MTHFR #Autism #ADHD #ChildrensHealth #Leucovorin #FunctionalMedicine #Pediatrics Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even infertility. Genetics play a big role—there are 17 SNPs that can lock homocysteine in place—but vitamin deficiencies can make it worse. The real breakthrough isn’t lowering homocysteine itself but calming the cytokines it triggers, like IL-8 and MCP-1. That’s why VARS Glutathione, the only patented oral form proven to work, is so powerful—it lowers those cy

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the