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Gene referenceSep 23, 2026

SERPINE1 makes PAI-1, a protein involved in breaking down blood clots. You may also see PAI4G used for this pathway.

Report teachingSep 16, 2026

…PAI-1, encoded by SERPINE1, helps regulate the breakdown of clots by inhibiting tissue and urokinase plasminogen activators. The 4G/5G promoter variation is commonly identified as rs1799889. Follow the pathway Dr. Purser discusses fibrinol…

Books & reading guidesFrom the archive

…pieces connect When discussing estrogen, bring up clotting, blood pressure, cancer history, timing after menopause, and the route you are considering. The history shapes the hormone discussion The HRT document highlights timing after menop…

Learning essentialsSep 23, 2026
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How Dr. Purser combines inherited tendencies, current nutrient findings and conventional laboratory results without treating them as the same test.

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