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Genomic imprinting describes how some genes are regulated differently depending on which parent contributed them.

How the Purser approach moves from a nutrient finding to priorities, a manageable plan and reassessment.

Pulsatile secretion makes random GH difficult to interpret; stimulation/suppression testing may be needed.

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho

CMA and antioxidant or redox results describe different aspects of cellular nutrient function.

Dupilumab, sold as Dupixent, is a prescribed antibody medicine that acts on IL-4 receptor alpha.

Infliximab, sold as Remicade and as biosimilars, is a prescribed antibody medicine that targets TNF-alpha.

Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.

Jackson Larkin and Lois Schweigert explain the science, benefits, and real results of the VARS antioxidant protocol for inflammation, recovery, and long-term wellness.

A subscriber post from Purser Wellness on Substack, covering genetics and methylation, gut and digestion.

Why elevated soluble IL-2 receptor levels drive chronic inflammation and pain in sarcoidosis — and what actually helps quiet the fire

A post from Purser Wellness on Substack, covering inflammation and antioxidants, testing and nutrients.