Search results

RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene.

TGFB1 encodes transforming growth factor beta 1, which has roles in immune regulation, tissue repair and extracellular-matrix production. Its effects can include both regulation of inflammation and promotion of fibrosis.

TNFRSF10A encodes death receptor 4, or DR4, a receptor that can receive the TRAIL signal and participate in regulated cell-death pathways. TRAIL itself is encoded by TNFSF10.

Ever remember something I said in a video but have no idea which video it was? We’ve been working on that. Introducing **Purser Wellness Explore** a new home for my teaching, organized so you can find the subjects that matter to you. MTH

Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wrong . Every day that I run into abject medical ignorance—where medicine arrogantly refuses to bend to the hard truth of proven science—I remember Ignaz Semmelweis. Semmelweis died a broken pauper in an asylum, his life destroyed by the conventional doctors of his generation who refused to accept handwashing. Their dismissive attitude today stems not from mal

Good questions deserve a deeper conversation. Purser Wellness Explore is a new space to follow yours - videos, articles, and guided journeys with me. Start with MTHFR, cytokines, homocysteine, gut health… or whatever thread you’re holding

Explore D-amino acid oxidase activator (DAOA / G72), rs2391191, D-serine, NMDA receptors, glutamate signaling, and research questions about brain and mood.

Dan and Jackson discuss serum testing, intracellular nutrient results, REDOX, and the questions each kind of test addresses.

The MTHFR Sugar Crash Cycle. The answers to the answers to the problems no one else has ever been able to give you. Find the support and help you've been looking for at PurserWellness.com

A subscriber episode exploring questions about MTHFR, nutrient status, and daily energy. Read the public introduction and continue on Substack.

Dr. Purser’s subscriber report on MAO-A, genetic terminology, and the anxiety-related questions discussed in the public introduction.

Explore cytokines, chemokines, receptors, and related genes on the comprehensive panel, including CD40LG, IL18R1, DDAH1, RAD50, and SLC19A1.