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RAD50 encodes a DNA-repair protein. The surrounding genomic region also contains regulatory elements relevant to the nearby IL4, IL5 and IL13 cluster, so a locus association can concern more than the coding function of one gene. Also called…

See how homocysteine connects to cysteine and glutathione. Follow seven simple steps, explore the side routes, and tap a word or building block to learn more. Also called: Transsulfuration, Transsulphuration, Sulfur pathway, Cysteine synthe…

Ever remember something I said in a video but have no idea which video it was? We’ve been working on that. Introducing **Purser Wellness Explore** a new home for my teaching, organized so you can find the subjects that matter to you. MTH…

Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wr…

Explore multiple sclerosis (MS), central nervous system inflammation, myelin, symptoms, and related immune signals. Understand the connection Multiple sclerosis involves immune-mediated injury to myelin and other nervous-system structures.…

Explore eotaxin-1, CCR3, eosinophils, allergy, and respiratory and neurological conditions. Understand the connection CCL11, also called eotaxin-1, guides eosinophils toward tissues by signaling through CCR3. Eosinophils are immune cells i…

Explore interleukin-4, Th2 cells, immunoglobulin E (IgE), and allergic and atopic conditions. Understand the connection IL-4 helps organize type 2 immune responses and supports antibody switching toward IgE. This makes it relevant to aller…

…plore interleukin-6, C-reactive protein (CRP), the acute-phase response, rheumatoid arthritis, and related health conditions. Understand the connection IL-6 is an immune messenger that participates in inflammation, infection responses, and…

Why should supporting your body have to be one size fits all? Your body faces oxidative stress every day, both inside and out. So why limit yourself to only one way of supporting it? That is where VARS SOD and Rejuve come into the conve…

Explore high mobility group box 1, damage-associated molecular patterns (DAMPs), TLR4, RAGE, and cellular stress. Understand the connection HMGB1 normally helps organize DNA inside a cell. When it is released outside injured or stressed ce…

Explore Toll-like receptor 4, lipopolysaccharide (LPS), HMGB1, innate immune sensing, and related inflammatory pathways. Understand the connection TLR4 helps recognize bacterial lipopolysaccharide, or LPS, with assistance from CD14 and MD-…

Kickstart your health journey with us! 🌱 Enjoy 10% OFF your first order as a welcome gift to the Purser Wellness family. Use code HEALTHY10 at checkout and experience premium, physician-formulated supplements you can trust. Ready to …