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…a, a chemokine involved in attracting and activating immune cells. It is related to CCL4, or MIP-1 beta, but the two genes and proteins are distinct. Also called: MIP-1 alpha and the chemokine cluster CCL3 encodes MIP-1 alpha, a chemokine …

…codes MIP-1 beta, a chemokine involved in attracting immune cells. It participates in a recruitment network that includes CCL2, CXCL8 and related chemokines. Also called: MIP-1 beta and overlapping recruitment signals CCL4 encodes MIP-1 be…

… do my immune measurements fit? Variant IDs in the teaching reference: rs3092952 Also called: CD40 ligand, CD154 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may discuss MTHFR Daily and…

…cardiovascular teaching. Follow the connection through measured lipids, family history and overall cardiovascular risk. A SNP does not by itself select a CETP inhibitor or establish that HDL is low; medication decisions depend on the full c…

…dentified inflammatory process? Variant IDs in the teaching reference: rs4073, rs2227306, rs2227307 Also called: IL-8, Interleukin 8 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may dis…

…es or clot-prevention planning? Variant IDs in the teaching reference: rs6025 Also called: Factor V, Factor V Leiden

…s absent. A question to bring to your visit Is there a measured factor IX problem or a pathogenic finding that needs hematology review? Variant IDs in the teaching reference: rs6048 Also called: Factor IX

GSTO2 encodes glutathione S-transferase omega 2, a redox enzyme with dehydroascorbate reductase activity that connects glutathione chemistry with vitamin C recycling. It is a separate gene from GSTO1. Also called: A distinct member of the …

IFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses. Also called: Interferon gamma and macrophage activati…

IL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine. Also called: A shared component of two cytokines IL12B encodes the p40 subuni…

…pattern or a different problem? Variant IDs in the teaching reference: rs1800925, rs20541, rs1295686 Also called: IL-13, Interleukin 13 Where the VARS Triad and MTHFR Daily fit If you are exploring homocysteine or cytokines, Dr. Purser may …

…al’s risk. A question to bring to your visit How do my measured metabolic and cardiovascular risk factors fit this immune discussion? Variant IDs in the teaching reference: rs1946518 Also called: IL-18, Interleukin 18 Where the VARS Triad a…