The older Purser genetics reference uses the heading “DAOA (AOC1)” in its gut section.
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What’s searchable?DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.
Encodes an enzyme involved in fatty-acid metabolism.
Encodes an enzyme involved in fatty-acid metabolism.
FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step.
FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
FUT2 affects substances on the surfaces of the gut and other moist tissues and is studied in relation to the microbiome.
GAD1 helps your body make GABA, a chemical messenger, from glutamate.
GAD2 helps make GABA, a chemical messenger, from glutamate.
GCLC helps make glutathione, an antioxidant your body produces.
GCLM helps regulate one of the steps your body uses to make glutathione.
GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.
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