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Report teachingSep 16, 2026
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…in a wider network rather than the only cause of migraine. Follow the pathway His teaching connects cytokines, homocysteine, oxidative stress, and the trigeminal pain pathway. Conventional migraine discussions include triptans and CGRP-dir…

Report teachingSep 16, 2026
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…r when red blood cells do not survive as long as expected. Follow the pathway Dr. Purser discusses hemolysis, blood loss, transfusion, and other changes in red-cell turnover alongside true hypoglycemia. Kidney or liver conditions and certa…

Report teachingSep 16, 2026
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…s, imaging, and examination helps establish the diagnosis. Follow the pathway Dr. Purser discusses Th1 and Th17 cells, TNF-alpha, IL-6, IL-17, and oxidative stress around active lesions. He connects this with the blood–brain barrier and th…

Report teachingSep 16, 2026
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…s of folate used in one-carbon metabolism. These reactions support DNA building blocks and the pathways that move methyl groups through the body. Follow the pathway Dr. Purser discusses rs2236225 and rs1076991, folate forms, homocysteine r…

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…5G promoter variation is commonly identified as rs1799889. Follow the pathway Dr. Purser discusses fibrinolysis, the process of dissolving clots, alongside homocysteine and blood-vessel inflammation. These are interacting risk consideratio…

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…e cells and the cells that line tissues and blood vessels. Follow the pathway Dr. Purser connects TNF-alpha with joint, skin, and bowel inflammation, as well as oxidative stress. He discusses targeted TNF medicines and the separate role of…

Report teachingSep 16, 2026
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…n change over time and with stress or other circumstances. Follow the pathway Dr. Purser discusses cortico-striatal-thalamo-cortical circuits, dopamine, and inhibitory GABA signaling. He also explores behavioral therapy, medicines, and sel…

Report teachingAug 16, 2026
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… involved in allergies and defense against some parasites. Follow the pathway Dr. Purser connects eosinophil recruitment with allergic airway and skin inflammation. He also discusses research on CCL11 and brain aging; a research associatio…

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…an attract monocytes, eosinophils, and other immune cells. Follow the pathway Dr. Purser explains how repeated immune-cell recruitment can sustain tissue inflammation. His teaching connects this pathway with allergic inflammation and discu…

Report teachingAug 16, 2026
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… cells that remove debris and participate in inflammation. Follow the pathway Dr. Purser follows the CCL2–CCR2 pathway through blood-vessel, kidney, and metabolic inflammation. He discusses homocysteine, NF-κB signaling, and reactive oxyge…

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