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MTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss  article image
Health BlogApr 6, 2026

MTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation . This is not fringe theory. It is the clinical reality I hav

FacebookApr 6, 2026

Quick update!

Quick update! You can now access all of my HORMONE HEALTH Courses right on DanPurserMD.com! If you purchased one of my courses in the past on Udemy, reach out at dan@danpursermd.com and we will grant you access to the courses you've purch

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine article image
Health BlogMar 13, 2026

The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho

FacebookJun 24, 2025

🚨 Tired? Foggy? Achy? 🚨

🚨 Tired? Foggy? Achy? 🚨 You might be missing something big—and your standard blood test won't catch it. 👀 We’re talking about the CMA (Cellular Micronutrient Assay)—a super-accurate test that looks inside your cells to find deficiencies in

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