Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
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What’s searchable?Follow Dr. Purser’s discussion of folate metabolism and inflammation.
If you’ve been struggling with severe chronic fatigue, unexplained anxiety, or cardiovascular red flags, your genes might be trying to tell you something. Millions of patients walk out of traditional clinics with normal blood tests, only to be told their crippling symptoms are "all in their head." If you carry the C677T variant, you aren't crazy—you are dealing with a breakdown in cellular biochemistry. The Problem With Synthetic Folic Acid The standard advice from standard doctors is to take synthetic folic acid. For someone with the C677T genetic mutation, this is disastrous. Your enzyme pat
Your local doctor will likely tell you that MTHFR testing and taking an MTHFR Daily supplement is a waste of money. They might even claim it isn't a real medical issue. After 15 years of hearing this pap, I can tell you they are flat-out wrong . Every day that I run into abject medical ignorance—where medicine arrogantly refuses to bend to the hard truth of proven science—I remember Ignaz Semmelweis. Semmelweis died a broken pauper in an asylum, his life destroyed by the conventional doctors of his generation who refused to accept handwashing. Their dismissive attitude today stems not from mal
The MTHFR Sugar Crash Cycle. The answers to the answers to the problems no one else has ever been able to give you. Find the support and help you've been looking for at PurserWellness.com
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Instagram listingA subscriber episode exploring questions about MTHFR, nutrient status, and daily energy. Read the public introduction and continue on Substack.
Dan Purser MD and Jackson Larkin discuss the connections they consider between sugar cravings, cellular energy, and methylation.
🧬 MTHFR Mutations, High Homocysteine & Autoimmune Disease: The Hidden Root Cause Most Doctors Miss For decades, patients with RA, lupus, MS, Hashimoto’s, and fibromyalgia chase symptom relief with meds that never fix the underlying fire. A
A Guide by the World’s Leading Homocysteine Expert
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Health Blog listingDr. Purser shares his clinical perspective on homocysteine, methylation, and inflammatory patterns.
Jackson Larkin, Purser Wellness Nutritional Coach
A subscriber post from Purser Wellness on Substack, covering genetics and methylation, energy and metabolism.
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