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YouTube·YouTube publication: Jul 10, 2025

If you can’t convert homocysteine to glutathione bad things happen -inflammation and stroke risk. ⚠️

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Original sourceDan Purser MD on YouTube

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YouTube captions · Unreviewed · Imported 2026-09-23

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9 timestamped passages

0:03

We have a biotech aobiologics that creates super antioxidants based on the fact that most antioxidants out there and well I'd say almost all of them in the marketplace are oxidized pieces of garbage. Oxidized antioxidants that's like a gun that's been fired and emptied. Doesn't really work. And some

0:19

people can't reload it genetically. That's why you have the deficiency and the only way it shows up is on that seder micronutrient assay. So we're always looking at that redux part because it's really important. But if you're have oxidized glutathione or you're low in glutathione on the first

0:35

part of that to say the micronutrient assay, if you're low in glutathione, you got bigger problems. You're not just low in glutathione. Chances are you probably have something in your system that you've been genetically born with chewing up your your glutathione. There's a reason why you're depleted in

0:51

glutathione and you'll have brain fog. You'll feel terrible. you'll be tired and you feel toxic all the time. You get a lot of inflammation. It could be a homoyine problem and that's really where we've been focusing lately cuz 30% of the population has a high homocyine. It's arguable but it's the but I think

1:07

it's the number one cause of of endstage renal disease or kidney failure. So look around your family. Also causes strokes, heart attacks, blood clots. You'll have a high HSCP or high D-dimer or something like that that gives it away. That's what elevates your D- dimer and HSCP and

1:25

even Wesr is a high homocyine level because most doctors don't know any of this. They don't even check homoyine levels anymore because there's nothing you can do about it. You give glutathione cuz glutathione offsets the cytoines that homocyine causes to be

1:40

released. We have the only patented oral glutathione or vars glutathione. There's a reason why I say we have the only patented oral glutathione because we've proven it. It's validated. It meets the virus standard we created in validatable meaning you can prove it works absorbable meaning you can take it

1:56

either orally or topically that's glutil by Nan Patel my friend and so I'm involved with that one too the glutil is amazing it's a sprayon topical kind but you need first pass effect through your liver for a number of reasons so our oral glutathione we think is more

2:12

appropriate for this situation if you don't have glutathione in your system there's a reason why you got to dig deeper usually Usually I'm going to suggest genetics at that point. Try to figure out why you're chewing up that glutathione. Just the way my mind works. Why is it low? Anyway, this is Dr.

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DR. PURSER’S TREATMENT FRAMEWORK

The VARS Triad + MTHFR Daily

Dr. Purser places the VARS Triad—VARS Glutathione, VARS SOD and VARS Catalase—alongside MTHFR Daily at the center of his homocysteine and cytokine support approach. He emphasizes VARS Glutathione as a foundational functional-support component across his genetic SNP teaching.

This describes the Purser approach; it is not an individualized prescription or proof that a product corrects a gene variant. Review formulation, tolerance and your current treatment with your clinician.

VARS Glutathione Capsules product packagingPHYSICIAN DESIGNEDVARS Glutathione CapsulesCapsule product informationView productVARS Liposomal Glutathione product packagingPHYSICIAN DESIGNEDVARS Liposomal GlutathioneLiquid product informationView productVARS SOD product packagingPHYSICIAN DESIGNEDVARS SODFormerly SOD BoosterView productVARS Catalase Support product packagingPHYSICIAN DESIGNEDVARS Catalase SupportProduct information & ingredientsView productPHYSICIAN DESIGNEDMTHFR DailyProduct information & ingredientsView product

Product and testing details from our practice and shop. Discuss what fits your needs with your clinician. Current labels, availability and pricing are shown on the linked pages.

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Homocysteine and methylation→

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Glutathione, from the beginning

Mentions glutathione in the captions.

Inflammation topicWatch at 0:19 ↗
Meet your antioxidant network

Mentions glutathione in the captions.

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Understanding inflammation

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Inflammation & antioxidants

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A note on the archive

These are the original author’s words and perspectives. Older material may reflect earlier teaching. Use the source and publication date for context.

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PURSER WELLNESSMTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss From the reading room
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MTHFR Mutations, Elevated Homocysteine & Autoimmune Inflammation: The Hidden Root Cause Most Doctors Miss

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation . This is not fringe theory. It is the clinical reality I hav

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The Hidden Molecule Driving Inflammation: Understanding the Purser Model of Homocysteine

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho

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PURSER WELLNESSHow To Know If You Have High Homocysteine?A conversation with Dr. Purser
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How To Know If You Have High Homocysteine?

High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the

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If you can’t convert homocysteine to glutathione bad things happen -inflammation and stroke risk. ⚠️ — Purser Wellness Explore