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YouTube·YouTube publication: Jun 14, 2025

What are the top genes I watch for when looking at our genetic panel? Do you have any of these?

GeneticsInflammation
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Original sourceDan Purser MD on YouTube

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0:01

Hey, this is Dr. Dan Perser here. What do I look for when I look through a genetic panel? These are things that will you if you don't find them or good for you. The first is homoyine. You have a genetic reason to have a high fix homocyine. So I dig into all the methylation stuff. I'm looking at MTRR,

0:18

MTR, the MTHFRs. They block the breakdown of homoyine to glutathione. Matter of fact, this is all about the transformation of homoyine to glutathione. If you're homozygous on any of those, you're going to have a high fixed homocyine level. So we got to deal

0:35

with that. We deal with that using the forest glutathione because the glutathione in there actually works. So actually lowers interlucan 8 and MCP-1. What you really want to follow, you can't change your homoyine even with the glutathione. It's stuck. But what it causes release of of two cytoines, the

0:52

main one being interlucanate ILA. It lowers that down to zero when you take enough of it. So you can follow that or have your doctor follow that for you. The next thing I look for is PMT. PMT if you're homozygous means you can't make enough phosphotylcholine. It can cause

1:08

you to have napp or fatty liver disease causes a nash then which go which is non-alcoholic stale hepatitis which means your liver is dying and getting really scarred up and then you liver dies. So you either get a transplant, you die or you get liver cancer. Those

1:23

kind of all go together. So that's the second thing I look for. What's the third thing? NR3C1 it's going to cause brain inflammation and shrinkage and dementia. You can't make fossil serarine. So remember PEMT you can't make fossil choline. NR3C1 you can't make fossil serarine for your brain.

1:39

There's also a lot of crossover between those. The fossil serarine can definitely help your liver and the fossil can definitely help your brain. The fourth thing I look for is sod errors. Sod one can cause ALS or luger's disease if you're missing it. Sod two can cause cancer and sod three causes

1:56

all the other inflammation in your body except for that caused by homocyine. So if someone has sod three and homocyine they have a lot of inflammation. They're going to be hurting. So we usually add the bar sod which also meets our bar standard. Bar sod capsules are amazing and they can bring down inflammation.

2:12

You'll feel it just like you'll feel it when your IL8 drops to normal or zero when you're taking the glutathione. Anyway, that's just my thoughts, but I just want to get that out there because I keep talking to patients about all this. So, thanks much for watching. It's Dr. Dan Person.

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