Encyclopedia

GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.

GPX1 helps cells use glutathione to handle peroxides.

GPX3 helps use glutathione in peroxide defense outside cells.

GPX4 helps protect cell membranes from certain peroxides.

GSR encodes glutathione reductase. It uses reducing power from NADPH to help convert oxidized glutathione back to reduced glutathione, allowing this antioxidant system to be reused.

GSTM1 helps your body use glutathione to process some compounds.

GSTO1 belongs to the omega family of glutathione S-transferases. These enzymes participate in redox chemistry, with roles that differ from the better-known GSTM1 and GSTP1 pathways.

GSTP1 helps your body use glutathione to process some compounds.

GSTT1 helps your body use glutathione to process some compounds.

HDC is the gene name for Histidine Decarboxylase. Learn what a specific result could mean and what to ask about it.

HFE helps regulate iron absorption through signaling that influences hepcidin. The commonly discussed C282Y and H63D variants correspond to rs1800562 and rs1799945. Their implications depend on the combination present and clinical findings.

HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type.