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Could the signals controlling your health be working for you... or against you? Most people have never heard of cytokines, yet these powerful cellular messengers play a critical role in how your body responds to stress, inflammation, recov

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, mind, mood, and sleep.

High homocysteine signals a broken transsulfuration pathway, leaving you unable to detox or convert it into glutathione. This shows up in conditions like PCOS and fibromyalgia, where patients often struggle with inflammation, pain, and even infertility. Genetics play a big role—there are 17 SNPs that can lock homocysteine in place—but vitamin deficiencies can make it worse. The real breakthrough isn’t lowering homocysteine itself but calming the cytokines it triggers, like IL-8 and MCP-1. That’s why VARS Glutathione, the only patented oral form proven to work, is so powerful—it lowers those cy

Most glutathione supplements fail because they break down before your body can use them. VARS Glutathione is different—it’s patented, validated, and proven to raise real intracellular glutathione levels. That means it actually works to calm inflammation, lower cytokines, and protect your cells where it matters most.

High homocysteine? It’s not the number—it’s the cytokines it triggers (like IL-8) that cause strokes, kidney failure & inflammation. We found 17 gene SNPs + 12 vitamin deficiencies that drive it—and VARS Glutathione helps shut it down.

Struggling with inflammation, high cytokines, or conditions like psoriasis, kidney disease, or chronic fatigue? The root cause could be elevated interleukins like IL-8 and MCP-1, often triggered by high homocysteine levels. The most powerful natural solution we’ve found?

Struggling with high blood pressure that just won’t budge—even with multiple meds? It might be due to genetic issues causing high homocysteine , which can stiffen your arteries through IL-8 and MCP-1 cytokines.

Superoxide Dismutase 3 (SOD 3), also known as extracellular SOD or ubiquitous SOD, plays a critical role in your body’s defense against inflammation and oxidative stress. Here’s why it matters: Stabilizes Mast Cells SOD 3 helps suppress mast cell activation, reducing the release of inflammatory mediators that contribute to conditions like skin inflammation, inflammatory bowel disease, and chronic pain. Reduces Pro-Inflammatory Cytokines By inhibiting cytokines like TNF-Alpha, SOD 3 can help soothe inflammation at its source. Supports Healthy Joints and Blood Vessels Whether you have joint disc

Doctor Purser talks about the diagnosis and treatments (most of which require your favorite hormone - Progesterone) of bad pelvic pain in women. Those of you with INTERSTITIAL CYSTITIS, ENDOMETRIOSIS, SEVERE PMS, or PELVIC INFLAMMATORY DISEASE can finally stop living your life in pain. Try these suggestions to improve your quality of life and reduce your pain levels! Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

Mast Cell Activation Syndrome (MCAS) often flares when oxidative stress is high, pushing mast cells to release histamine and inflammatory cytokines. Superoxide Dismutase (SOD) is your body’s first defense against that stress—neutralizing su

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.