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Explore enteric nerve development, aganglionosis, bowel function, RET, EDNRB, EDN3, SOX10, PHOX2B, and genetic syndromes discussed alongside Hirschsprung’s disease.

What if your standard blood work says everything looks normal, but you still do not feel like yourself? That is where a Cellular Micronutrient Assay, or CMA, can add another piece to the conversation. Your body depends on vitamins, minera

MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health. While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status

Every single day your cells face oxidative stress from normal metabolism, environmental exposures, exercise, stress, and aging. Your body has a defense for that. Superoxide dismutase, better known as SOD, is a powerful antioxidant enzyme

The goal is not to let your genetics define your future. It is to understand them. Because your genes may influence how your body functions, but knowledge gives you the opportunity to ask better questions, make more informed decisions, an

…he pathway Dr. Purser follows the CCL2–CCR2 pathway through blood-vessel, kidney, and metabolic inflammation. He discusses homocysteine, NF-κB signaling, and reactive oxygen species as interacting parts of this picture, alongside glutathion…

…cts the initial recognition of a trigger with inflammation, blood-vessel and joint research, and the antioxidant network. Bring these questions to your visit Ask which result is being discussed: a genetic variant, a measured protein level,…

Purser Wellness Coach Justace explains why looking at genetics alongside nutritional testing may help you ask better questions and make more informed decisions about your health. Because personalized wellness should not begin with guessing

What if your blood work says everything is normal, but you still do not feel normal? That is exactly why the conversation about Cellular Micronutrient Assay testing matters. Your body depends on vitamins, minerals, amino acids, and antiox

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

A subscriber post from Purser Wellness on Substack, covering genetics and methylation, inflammation and antioxidants.

Discover the incredible power of your blood vessels! From nourishing every cell to supporting your overall health, these tiny highways are truly magical. Ready to learn how to keep them strong?